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Recruiting Phase 3 Interventional

A Global Study to Assess the Effects of Durvalumab + Domvanalimab Following Concurrent Chemoradiation in Participants With Stage III Unresectable NSCLC

ClinicalTrials.gov ID: NCT05211895

Public ClinicalTrials.gov record NCT05211895. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 5, 2026, 4:30 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III, Randomised, Double-blind, Placebo-controlled, Multicentre, International Study of Durvalumab Plus Domvanalimab(AB154) in Participants With Locally Advanced (Stage III), Unresectable Non-small Cell Lung Cancer Whose Disease Has Not Progressed Following Definitive Platinum-based Concurrent Chemoradiation Therapy

Study identification

NCT ID
NCT05211895
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
AstraZeneca
Industry
Enrollment
860 participants

Conditions and interventions

Interventions

  • Domvanalimab Drug
  • Durvalumab Drug
  • Placebo Other

Drug · Other

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 17, 2022
Primary completion
Jul 11, 2028
Completion
Sep 30, 2030
Last update posted
Apr 22, 2026

2022 – 2030

United States locations

U.S. sites
43
U.S. states
23
U.S. cities
40
Facility City State ZIP Site status
Research Site Chandler Arizona 85224 Recruiting
Research Site Phoenix Arizona 85054 Suspended
Research Site Fountain Valley California 92708 Recruiting
Research Site Santa Rosa California 95403 Recruiting
Research Site Washington D.C. District of Columbia 20016 Recruiting
Research Site Jacksonville Florida 32224 Suspended
Research Site Orlando Florida 32804 Recruiting
Research Site Saint Augustine Florida 32086 Recruiting
Research Site Macon Georgia 31217 Suspended
Research Site Elmhurst Illinois 60126 Suspended
Research Site Maywood Illinois 60153 Withdrawn
Research Site Naperville Illinois 60540 Withdrawn
Research Site Louisville Kentucky 40202 Suspended
Research Site Baltimore Maryland 21224 Recruiting
Research Site Silver Spring Maryland 20910 Suspended
Research Site Ann Arbor Michigan 48106-0995 Recruiting
Research Site Detroit Michigan 48202 Completed
Research Site Minneapolis Minnesota 55407 Recruiting
Research Site Rochester Minnesota 55905 Suspended
Research Site Reno Nevada 89511 Recruiting
Research Site East Brunswick New Jersey 08816 Recruiting
Research Site Florham Park New Jersey 07932 Withdrawn
Research Site Buffalo New York 14221 Withdrawn
Research Site Johnson City New York 13790 Withdrawn
Research Site Asheville North Carolina 28805 Withdrawn
Research Site Asheville North Carolina 28806 Withdrawn
Research Site Charlotte North Carolina 28204 Withdrawn
Research Site Winston-Salem North Carolina 27157 Withdrawn
Research Site Columbus Ohio 43214 Recruiting
Research Site Columbus Ohio 43219 Withdrawn
Research Site Maumee Ohio 43537 Recruiting
Research Site Oklahoma City Oklahoma 73102 Recruiting
Research Site Pittsburgh Pennsylvania 15212 Recruiting
Research Site Charleston South Carolina 29401 Suspended
Research Site Chattanooga Tennessee 37404 Recruiting
Research Site Nashville Tennessee 37203 Recruiting
Research Site Nashville Tennessee 37232 Suspended
Research Site Fort Sam Houston Texas 78234 Recruiting
Research Site Kingwood Texas 77339 Withdrawn
Research Site Arlington Virginia 22205 Recruiting
Research Site Fort Belvoir Virginia 22060 Recruiting
Research Site Spokane Valley Washington 99216 Recruiting
Research Site Appleton Wisconsin 54911 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 219 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05211895, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 22, 2026 · Synced May 5, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05211895 live on ClinicalTrials.gov.

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