Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection
Public ClinicalTrials.gov record NCT05219110. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Hyperhydration to Improve Kidney Outcomes in Children With Shiga Toxin-Producing E. Coli Infection: A Multinational Embedded Cluster Crossover Randomized Trial
Study identification
- NCT ID
- NCT05219110
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Not applicable
- Lead sponsor
- University of Calgary
- Other
- Enrollment
- 1,040 participants
Conditions and interventions
Interventions
- Infusion of 200% maintenance fluids as balanced crystalloid IV solution Other
- Oral fluids; infusion of up to 110% maintenance fluids as balanced crystalloid IV solution Other
Other
Eligibility (public fields only)
- Age range
- 9 Months to 21 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 28, 2022
- Primary completion
- Aug 30, 2026
- Completion
- Aug 30, 2027
- Last update posted
- Jun 4, 2025
2022 – 2027
United States locations
- U.S. sites
- 22
- U.S. states
- 18
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | Recruiting |
| Arkansas Children's Hospital | Little Rock | Arkansas | 72202 | Recruiting |
| University of California, San Diego | La Jolla | California | 92093 | Recruiting |
| University of California, Davis | Sacramento | California | 95817 | Recruiting |
| University of Colorado Denver | Denver | Colorado | 80045 | Recruiting |
| Children's Research Institute | Washington D.C. | District of Columbia | 20010 | Recruiting |
| Emory University | Atlanta | Georgia | 30322 | Recruiting |
| Indiana University Children's Hospital | Indianapolis | Indiana | 47401 | Recruiting |
| University of Kentucky | Lexington | Kentucky | 40526 | Recruiting |
| Norton Children's Hospital | Louisville | Kentucky | 40202 | Recruiting |
| Children's Minnesota Hospital | Minneapolis | Minnesota | 55404 | Recruiting |
| Washington University | St Louis | Missouri | 63110 | Recruiting |
| Children's Hospital Medical Center | Cincinnati | Ohio | 45229-3039 | Recruiting |
| University Hospitals Rainbow Babies & Children's Hospital | Cleveland | Ohio | 44106 | Recruiting |
| Nationwide Children's Hospital | Columbus | Ohio | 43205 | Recruiting |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | Recruiting |
| Oregon Health & Science University | Portland | Oregon | 97239 | Recruiting |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | Recruiting |
| Vanderbilt Children's Hospital | Nashville | Tennessee | 43205 | Recruiting |
| Baylor College of Medicine | Houston | Texas | 77030 | Recruiting |
| University of Utah | Salt Lake City | Utah | 84112 | Recruiting |
| Seattle Children's Hospital | Seattle | Washington | 98105 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 4 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05219110, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 4, 2025 · Synced May 8, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05219110 live on ClinicalTrials.gov.