Safety, PK, PD, Clinical Activity of KT-333 in Adult Patients With Refractory Lymphoma, Large Granular Lymphocytic Leukemia, Solid Tumors
Public ClinicalTrials.gov record NCT05225584. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1, Multicenter, Open-Label, Dose-Escalation and Expansion Study to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of Intravenously Administered KT-333 in Adult Patients With Relapsed or Refractory Lymphomas, Large Granular Lymphocytic Leukemia, and Solid Tumors
Study identification
- NCT ID
- NCT05225584
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- Kymera Therapeutics, Inc.
- Industry
- Enrollment
- 56 participants
Conditions and interventions
Conditions
Interventions
- KT-333 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 18, 2022
- Primary completion
- Mar 2, 2025
- Completion
- Mar 2, 2025
- Last update posted
- Mar 18, 2025
2022 – 2025
United States locations
- U.S. sites
- 13
- U.S. states
- 11
- U.S. cities
- 12
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UC Irvine Health-Chao Family Comprehensive Cancer Center | Orange | California | 92868-3201 | — |
| Norton Cancer Institute | Louisville | Kentucky | 40207 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Hackensack University Medical Center, John Theurer Cancer Center | Hackensack | New Jersey | 07601 | — |
| Montefiore Medical Center, The University Hospital for Albert Einstein College of Medicine | The Bronx | New York | 10467 | — |
| The Christ Hospital Cancer Center | Cincinnati | Ohio | 45219 | — |
| Ohio State University Wexner Medical Center | Columbus | Ohio | 43210-1240 | — |
| Abramson Cancer Center of the University of Pennsylvania Perelman Center for Advanced Medicine | Philadelphia | Pennsylvania | 19104 | — |
| Thomas Jefferson University, Sidney Kimmel Cancer Center | Philadelphia | Pennsylvania | 19107 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| University of Virginia, Emily Couric Cancer Center | Charlottesville | Virginia | 22903 | — |
| University of WA/Seattle Cancer Care Alliance | Seattle | Washington | 98195 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05225584, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 18, 2025 · Synced May 20, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05225584 live on ClinicalTrials.gov.