ACTEMRA® for the Treatment of Pediatric Adamantinomatous Craniopharyngioma

ClinicalTrials.gov ID: NCT05233397

Public ClinicalTrials.gov record NCT05233397. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 16, 2026, 9:19 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase 2 Study of Systemic IL-6 Receptor Antagonist ACTEMRA® (Tocilizumab) for the Treatment of Progressive/Recurrent Pediatric Adamantinomatous Craniopharyngioma

Study identification

NCT ID: NCT05233397
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: Nationwide Children's Hospital; Other
Enrollment: 30 participants

Conditions and interventions

Conditions

Interventions

Tocilizumab Drug

Drug

Eligibility (public fields only)

Age range: 1 Year to 39 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Dec 15, 2022
Primary completion: Nov 30, 2027
Completion: Nov 30, 2029
Last update posted: Apr 22, 2026

2022 – 2029

United States locations

U.S. sites: 8
U.S. states: 7
U.S. cities: 8

Facility	City	State	ZIP	Site status
Children's Hospital Colorado	Aurora	Colorado	80045	Recruiting
Children's National Medical Center	Washington D.C.	District of Columbia	20010	Recruiting
Nicklaus Children's Hospital	Miami	Florida	33155	Active, not recruiting
Duke Children's Hospital	Durham	North Carolina	27710	Recruiting
Cincinnati Children's Hospital Medical Center	Cincinnati	Ohio	45229	Recruiting
Nationwide Children's Hospital	Columbus	Ohio	43235	Recruiting
Texas Children's Hospital	Houston	Texas	77030	Recruiting
Seattle Children's Hospital	Seattle	Washington	98105	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT05233397, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 22, 2026 · Synced May 16, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05233397 live on ClinicalTrials.gov.

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