Safety and Efficacy of BHV-3000 (Rimegepant) Orally Disintegrating Tablet for the Acute Treatment of Chronic Rhinosinusitis
Public ClinicalTrials.gov record NCT05248997. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Official title
A Phase 2/3, Double-Blind, Randomized, Placebo-Controlled, Safety and Efficacy Trial of BHV-3000 (Rimegepant) Orally Disintegrating Tablet (ODT) for the Acute Treatment of Chronic Rhinosinusitis (CRS) With or Without Nasal Polyps
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to compare the efficacy and safety of rimegepant versus placebo in the acute treatment of chronic rhinosinusitis (CRS) with and without nasal polyps.
Study identification
- NCT ID
- NCT05248997
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 261 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 17, 2022 (Actual)
- Primary completion
- Mar 11, 2024 (Actual)
- Completion
- Apr 2, 2024 (Actual)
- Last update posted
- Mar 26, 2025
2022 – 2024
United States locations
- U.S. sites
- 33
- U.S. states
- 14
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| San Diego Clinical Research Center | La Mesa | California | 91942 | — |
| Velocity Clinical San Diego | La Mesa | California | 91942 | — |
| National Research Institute | Panorama City | California | 91402 | — |
| Sacramento Ear Nose and Throat Surgical and Medical Group, Inc. | Roseville | California | 95628 | — |
| Sharp & Children's MRI Center, LLC (CT scan) | San Diego | California | 92123 | — |
| Breathe Clear Institute | Torrance | California | 90503 | — |
| Colorado ENT & Allergy | Colorado Springs | Colorado | 80923 | — |
| Velocity Clinical Research, New Smyrna Beach | Edgewater | Florida | 32132 | — |
| The Medici Medical Research, LLC | Hollywood | Florida | 33021 | — |
| Avantis Clinical Research | Miami | Florida | 33155 | — |
| Clinovation Research | Pompano Beach | Florida | 33064 | — |
| Treasure Valley Medical Research | Boise | Idaho | 83706 | — |
| ChicagoENT | Chicago | Illinois | 60657 | — |
| Kentuckiana Ear, Nose & Throat | Louisville | Kentucky | 40205 | — |
| Best Clinical Trials, LLC (Administrative Only) | New Orleans | Louisiana | 70115 | — |
| George Stanley Walker, MD | New Orleans | Louisiana | 70115 | — |
| University of Missouri Hospital & Clinics, ENT & Allergy Center of Missouri | Columbia | Missouri | 65201 | — |
| University of Missouri Healthcare - Investigational Pharmacy | Columbia | Missouri | 65212 | — |
| University of Missouri Hospital (Radiology) | Columbia | Missouri | 65212 | — |
| Clinvest Research, LLC | Springfield | Missouri | 65810 | — |
| St Charles Clinical Research | Weldon Spring | Missouri | 63304 | — |
| Northwell Health Department of Otolaryngology | New Hyde Park | New York | 11042 | — |
| Tekton Research, Inc. | Edmond | Oklahoma | 73013 | — |
| Allergy, Asthma & Clinical Research Center | Oklahoma City | Oklahoma | 73120 | — |
| Vital Prospects Clinical Research Institute, P.C. | Tulsa | Oklahoma | 74136 | — |
| Velocity Clinical Research, Grants Pass | Grants Pass | Oregon | 97527 | — |
| Velocity Clinical Research, Medford | Medford | Oregon | 97504 | — |
| Velocity Clinical Research, Anderson | Anderson | South Carolina | 29621 | — |
| Carolina ENT Clinic/CENTRI Inc. | Orangeburg | South Carolina | 29118 | — |
| Spokane Ear, Nose & Throat/ Columbia Surgical Specialists | Spokane | Washington | 99201 | — |
| Principle Research Solutions | Spokane | Washington | 99204 | — |
| Spokane Ear, Nose & Throat / Columbia Surgical Specialists | Spokane | Washington | 99216 | — |
| Allergy, Asthma & Sinus Center, S.C. | Greenfield | Wisconsin | 53228 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05248997, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 26, 2025 · Synced Nov 9, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05248997 live on ClinicalTrials.gov.