GM-CSF for Reversal of Immunoparalysis in Pediatric Sepsis-induced MODS
Public ClinicalTrials.gov record NCT05266001. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The GRACE-2 study is a prospective, multi-center, double-blind, randomized controlled trial of the drug GM-CSF vs placebo in children with sepsis-induced multiple organ dysfunction syndrome (MODS) who have immunoparalysis with mild to moderate inflammation.
Study identification
- NCT ID
- NCT05266001
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 141 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 1 Day to 17 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 14, 2022 (Actual)
- Primary completion
- Sep 10, 2025 (Actual)
- Completion
- Sep 10, 2025 (Actual)
- Last update posted
- Apr 9, 2026
2022 – 2025
United States locations
- U.S. sites
- 25
- U.S. states
- 15
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arkansas Children's Hospital | Little Rock | Arkansas | 72202 | — |
| Children's Hospital of Los Angeles | Los Angeles | California | 90027 | — |
| Benioff Children's Hospital - Oakland | Oakland | California | 64609 | — |
| Children's Hospital of Orange County | Orange | California | 92868 | — |
| University of California - Davis | Sacramento | California | 95618 | — |
| Benioff Children's Hospital - Mission Bay | San Francisco | California | 94143 | — |
| Children's Hospital Colorado | Aurora | Colorado | 80045 | — |
| Children's National Medical Center | Washington D.C. | District of Columbia | 20010 | — |
| CS Mott Children's Hospital | Ann Arbor | Michigan | 48109 | — |
| Children's Hospital of Michigan | Detroit | Michigan | 48202 | — |
| Children's Hospital of Minnesota | Minneapolis | Minnesota | 55404 | — |
| University of Minnesota | Minneapolis | Minnesota | 55455 | — |
| Mercy Children's Hospital | Kansas City | Missouri | 64108 | — |
| Duke University | Durham | North Carolina | 27705 | — |
| Rainbow Babies and Children's Hospital | Cleveland | Ohio | 44106 | — |
| Nationwide Children's Hospital | Columbus | Ohio | 43205 | — |
| Pennsylvania State University | Hershey | Pennsylvania | 17033 | — |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| Children's Hospital of Pittsburgh | Pittsburgh | Pennsylvania | 15260 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Texas Children's Hospital | Houston | Texas | 77030 | — |
| Children's Hospital of San Antonio | San Antonio | Texas | 78207 | — |
| Primary Children's Hospital | Salt Lake City | Utah | 84158 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23298 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53233 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05266001, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 9, 2026 · Synced Oct 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05266001 live on ClinicalTrials.gov.