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Recruiting Phase 2Phase 3 Interventional

Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS

ClinicalTrials.gov ID: NCT05267821

Public ClinicalTrials.gov record NCT05267821. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 19, 2026, 9:50 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS (TRIPS)

Study identification

NCT ID
NCT05267821
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 2, Phase 3
Lead sponsor
Nationwide Children's Hospital
Other
Enrollment
500 participants

Conditions and interventions

Interventions

  • Anakinra Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
1 Day to 17 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 13, 2022
Primary completion
May 14, 2028
Completion
Aug 30, 2028
Last update posted
Mar 12, 2026

2022 – 2028

United States locations

U.S. sites
32
U.S. states
18
U.S. cities
31
Facility City State ZIP Site status
Children's of Alabama Birmingham Alabama 35233 Recruiting
Arkansas Children's Hospital Little Rock Arkansas 72202 Recruiting
Children's Hospital of Los Angeles Los Angeles California 90027 Recruiting
Benioff Children's Hospital - Oakland Oakland California 64609 Recruiting
Children's Hospital of Orange County Orange California 92868 Not yet recruiting
University of California, Davis Sacramento California 95817 Recruiting
Rady Children's Hospital San Diego California 92123 Recruiting
Benioff Children's Hospital - Mission Bay San Francisco California 94143 Recruiting
Children's Hospital Colorado Aurora Colorado 80045 Recruiting
Children's National Medical Center Washington D.C. District of Columbia 20010 Recruiting
Children's Hospital of Atlanta Atlanta Georgia 30329 Recruiting
Riley Children's Hospital Indianapolis Indiana 46204 Recruiting
CS Mott Children's Hospital Ann Arbor Michigan 48109 Recruiting
Children's Hospital of Michigan Detroit Michigan 48201 Recruiting
Children's Hospital of Minnesota Minneapolis Minnesota 55404 Not yet recruiting
University of Minnesota Minneapolis Minnesota 55455 Recruiting
Mercy Children's Hospital Kansas City Missouri 64108 Recruiting
Duke University Durham North Carolina 27705 Recruiting
Akron Children's Hospital Akron Ohio 44308 Recruiting
Cincinnati Children's Hospital Medical Center Cincinnati Ohio 45229 Recruiting
Rainbow Babies and Children's Hospital Cleveland Ohio 44106 Recruiting
Nationwide Children's Hospital Columbus Ohio 43205 Recruiting
Pennsylvania State University Hershey Pennsylvania 17033 Recruiting
Children's Hospital of Philadelphia Philadelphia Pennsylvania 19104 Recruiting
Children's Hospital of Pittsburgh Pittsburgh Pennsylvania 15260 Recruiting
Medical University of South Carolina Charleston South Carolina 29425 Recruiting
University of Texas Southwestern Dallas Texas 75390 Recruiting
Texas Children's Hospital Houston Texas 77030 Recruiting
Children's Hospital of San Antonio San Antonio Texas 78207 Recruiting
Primary Children's Hospital Salt Lake City Utah 84158 Recruiting
Virginia Commonwealth University Richmond Virginia 23298 Recruiting
Medical College of Wisconsin Milwaukee Wisconsin 53233 Not yet recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05267821, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 12, 2026 · Synced May 19, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05267821 live on ClinicalTrials.gov.

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