A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Participants With Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease
Public ClinicalTrials.gov record NCT05271409. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab as Monotherapy or in Addition to Baseline Therapy in Patients With Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease (MOGAD)
Study identification
- NCT ID
- NCT05271409
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Hoffmann-La Roche
- Industry
- Enrollment
- 152 participants
Conditions and interventions
Interventions
- Placebo Other
- Satralizumab Drug
Other · Drug
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 29, 2022
- Primary completion
- Nov 19, 2025
- Completion
- May 19, 2028
- Last update posted
- May 7, 2026
2022 – 2028
United States locations
- U.S. sites
- 23
- U.S. states
- 19
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35233 | Active, not recruiting |
| Mayo Clinic- Scottsdale | Scottsdale | Arizona | 85259 | Withdrawn |
| University of California Irvine - Manchester Pavilion | Irvine | California | 92697 | Active, not recruiting |
| University of Colorado - Anschutz Medical Campus (University of Colorado Health Sciences Center) | Aurora | Colorado | 80045 | Active, not recruiting |
| Medstar Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | Active, not recruiting |
| University of Florida College of Medicine Gainesville | Gainesville | Florida | 32608 | Active, not recruiting |
| Nemours Children's Clinic - of the Nemours Foundation | Jacksonville | Florida | 32207 | Withdrawn |
| Meridian Clinical Research, LLC | Savannah | Georgia | 31406 | Withdrawn |
| Northwestern University | Chicago | Illinois | 60611 | Withdrawn |
| Consultants in Neurology Ltd | Northbrook | Illinois | 60062 | Withdrawn |
| Johns Hopkins | Baltimore | Maryland | 21287 | Active, not recruiting |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | Recruiting |
| Memorial Healthcare Institute for Neurosciences and Multiple Sclerosis | Owosso | Michigan | 48867 | Active, not recruiting |
| Mayo Clinic - Rochester | Rochester | Minnesota | 55902 | Active, not recruiting |
| Washington University School of Medicine in St. Louis | St Louis | Missouri | 63110 | Active, not recruiting |
| NYU Langone | New York | New York | 10003 | Active, not recruiting |
| Duke University Medical Center | Durham | North Carolina | 27710 | Withdrawn |
| University of Cincinnati | Cincinnati | Ohio | 45267 | Active, not recruiting |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44915 | Active, not recruiting |
| OhioHealth Research Institute | Columbus | Ohio | 43214 | Withdrawn |
| Premier Neurology | Greenville | South Carolina | 29605 | Completed |
| Baylor College of Medicine | Houston | Texas | 77030 | Withdrawn |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | Completed |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 59 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05271409, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 7, 2026 · Synced May 10, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05271409 live on ClinicalTrials.gov.