Adjunctive GNX Treatment Compared With Placebo in Children and Adults With TSC-related Epilepsy
Public ClinicalTrials.gov record NCT05323734. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Double-blind, Randomized, Placebo-controlled Trial of Adjunctive Ganaxolone (GNX) Treatment in Children and Adults With Tuberous Sclerosis Complex (TSC)-Related Epilepsy (TrustTSC)
Study identification
- NCT ID
- NCT05323734
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Marinus Pharmaceuticals
- Industry
- Enrollment
- 129 participants
Conditions and interventions
Conditions
Interventions
- Ganaxolone Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 1 Year to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 31, 2022
- Primary completion
- Sep 8, 2024
- Completion
- Oct 13, 2024
- Last update posted
- Jul 10, 2025
2022 – 2024
United States locations
- U.S. sites
- 23
- U.S. states
- 16
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arkansas Children's Research Institute | Little Rock | Arkansas | 72202 | — |
| UCLA Mattel Children's Hospital, TSC Center | Los Angeles | California | 90095 | — |
| Children's Hospital of Orange County | Orange | California | 92868 | — |
| University of California, San Diego | San Diego | California | 92123 | — |
| Childrens Hospital Colorado | Aurora | Colorado | 80045 | — |
| Nemours Children's Hospital - Delaware Valley | Wilmington | Delaware | 19803 | — |
| University of Florida Gainesville | Gainesville | Florida | 32608 | — |
| Nemours Children's Health | Jacksonville | Florida | 32207 | — |
| Mid-Atlantic Epilepsy and Sleep Center | Bethesda | Maryland | 20817 | — |
| Mayo Clinic - Rochester | Rochester | Minnesota | 55905 | — |
| Children's Mercy Hosptial | Kansas City | Missouri | 64108 | — |
| University of Rochester Medical Center | Rochester | New York | 14642 | — |
| University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | 27599 | — |
| Atrium Health/Levine Children's Hospital | Charlotte | North Carolina | 28207 | — |
| Duke University Medical Center | Durham | North Carolina | 27712 | — |
| Cincinnati Children's Hospital Medical Center | Cincinnati | Ohio | 45229 | — |
| Penn State Children's Hospital | Hershey | Pennsylvania | 17033 | — |
| Le Bonheur Children's Hospital | Memphis | Tennessee | 38103 | — |
| Child Neurology Consultants of Austin (CNCA) | Austin | Texas | 78757 | — |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75207 | — |
| McGovern Medical School at the University of Texas Health Science Center | Houston | Texas | 77030 | — |
| University of Utah Health Care-Pediatric Neurology | Salt Lake City | Utah | 84108 | — |
| Seattle Children's Hospital | Seattle | Washington | 98105 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 40 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05323734, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 10, 2025 · Synced May 16, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05323734 live on ClinicalTrials.gov.