Mechanistic Study of the Effect of Itepekimab on Airway Inflammation in Patients With COPD
Public ClinicalTrials.gov record NCT05326412. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2a, Open-label, Two-part Study to Evaluate the Mechanism of Action of Itepekimab (Anti-IL-33 mAb) on Airway Inflammation in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Study identification
- NCT ID
- NCT05326412
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Sanofi
- Industry
- Enrollment
- 49 participants
Conditions and interventions
Conditions
Interventions
- Itepekimab SAR440340 Drug
Drug
Eligibility (public fields only)
- Age range
- 40 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 18, 2022
- Primary completion
- Mar 4, 2025
- Completion
- Jul 24, 2025
- Last update posted
- Mar 10, 2026
2022 – 2025
United States locations
- U.S. sites
- 11
- U.S. states
- 9
- U.S. cities
- 11
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UCLA Medical Center - Harbor- Site Number : 8400006 | Torrance | California | 90509 | — |
| National Jewish Health Medical Center- Site Number : 8400012 | Denver | Colorado | 80206 | — |
| University of Miami UHealth Tower- Site Number : 8400015 | Miami | Florida | 33125 | — |
| Harvard Medical School - Massachusetts General Hospital (MGH) - Medical Practice Evaluation Center (MPEC)- Site Number : 8400007 | Boston | Massachusetts | 02114 | — |
| Pulmonary and Medicine Associates- Site Number : 8400020 | Warren | Michigan | 48088 | — |
| University of Kansas Medical Center- Site Number : 8400004 | Kansas City | Missouri | 66160 | — |
| Allergy, Asthma and Clinical Research- Site Number : 8400010 | Oklahoma City | Oklahoma | 73120 | — |
| Clinical Research Associates of Central PA - Dubois- Site Number : 8400011 | DuBois | Pennsylvania | 15801 | — |
| Penn Medicine: University of Pennsylvania Health System- Site Number : 8400016 | Philadelphia | Pennsylvania | 19104 | — |
| University of Texas - Southwestern Medical Center- Site Number : 8400014 | Dallas | Texas | 75390 | — |
| University of Texas Medical Branch- Site Number : 8400001 | Galveston | Texas | 77555 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 17 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05326412, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 10, 2026 · Synced May 20, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05326412 live on ClinicalTrials.gov.