ClinicalTrials.gov record
Recruiting Phase 3 Interventional

Depemokimab in Participants With Hypereosinophilic Syndrome, Efficacy, and Safety Trial

ClinicalTrials.gov ID: NCT05334368

Public ClinicalTrials.gov record NCT05334368. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 20, 2026, 7:17 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-blind, Placebo-controlled Study to Investigate the Efficacy and Safety of Depemokimab in Adults With Hypereosinophilic Syndrome (HES)

Study identification

NCT ID
NCT05334368
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
GlaxoSmithKline
Industry
Enrollment
123 participants

Conditions and interventions

Interventions

  • Depemokimab Drug
  • Placebo Other

Drug · Other

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 5, 2022
Primary completion
Dec 18, 2028
Completion
Dec 18, 2028
Last update posted
Nov 24, 2025

2022 – 2028

United States locations

U.S. sites
11
U.S. states
10
U.S. cities
11
Facility City State ZIP Site status
GSK Investigational Site San Diego California 920237 Recruiting
GSK Investigational Site Atlanta Georgia 30322 Recruiting
GSK Investigational Site Boston Massachusetts 02111 Recruiting
GSK Investigational Site Southfield Michigan 48075 Withdrawn
GSK Investigational Site Rochester Minnesota 55905 Withdrawn
GSK Investigational Site Manhasset New York 11030 Completed
GSK Investigational Site Cincinnati Ohio 45229 Recruiting
GSK Investigational Site Columbus Ohio 43212 Recruiting
GSK Investigational Site Charleston South Carolina 29425 Recruiting
GSK Investigational Site Nashville Tennessee 37208 Completed
GSK Investigational Site Salt Lake City Utah 84132 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 80 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05334368, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 24, 2025 · Synced May 20, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05334368 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →