A Study of XMT-1660 in Participants With Solid Tumors
Public ClinicalTrials.gov record NCT05377996. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1, First-in-human, Dose Escalation and Expansion, Multicenter Study of XMT-1660 in Participants With Solid Tumors
Study identification
- NCT ID
- NCT05377996
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- Mersana Therapeutics
- Industry
- Enrollment
- 319 participants
Conditions and interventions
Conditions
Interventions
- XMT-1660 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 14, 2022
- Primary completion
- Nov 30, 2026
- Completion
- Apr 30, 2027
- Last update posted
- Apr 13, 2026
2022 – 2027
United States locations
- U.S. sites
- 26
- U.S. states
- 17
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic Comprehensive Cancer Center | Phoenix | Arizona | 85054 | Recruiting |
| UC Irvine Health-Chao Family Comprehensive Cancer Center | Orange | California | 92868 | Recruiting |
| UCSF Helen Diller Family Comprehensive Cancer Center | San Francisco | California | 94158 | Recruiting |
| UCLA David Geffen School of Medicine, Division of Hematology/Oncology | Santa Monica | California | 90404 | Recruiting |
| Mayo Clinic - Jacksonville | Jacksonville | Florida | 32224 | Recruiting |
| Florida Cancer Specialists | Sarasota | Florida | 34232 | Recruiting |
| Moffitt Cancer Center | Tampa | Florida | 33612 | Recruiting |
| Winship Cancer Institute, Emory University | Atlanta | Georgia | 30322 | Recruiting |
| Northwestern University | Chicago | Illinois | 60611 | Recruiting |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | Recruiting |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | Recruiting |
| Henry Ford Health Hospital | Detroit | Michigan | 48202 | Recruiting |
| Mayo Clinic - Rochester | Rochester | Minnesota | 55905 | Recruiting |
| Comprehensive Cancer Centers of Nevada | Las Vegas | Nevada | 89169 | Recruiting |
| New York University Langone Health | New York | New York | 10016 | Recruiting |
| ICHAN School of Medicine at Mount Sinai | New York | New York | 10029 | Not yet recruiting |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | Recruiting |
| Stephenson Cancer Center Oklahoma University Health | Oklahoma City | Oklahoma | 73104 | Recruiting |
| Avera Cancer Institute | Sioux Falls | South Dakota | 57105 | Recruiting |
| Sarah Cannon Research Institute (SCRI) | Nashville | Tennessee | 37203 | Recruiting |
| Texas Oncology, P.A. | Dallas | Texas | 75251 | Recruiting |
| MD Anderson | Houston | Texas | 77030 | Recruiting |
| Huntsman Cancer Institute | Salt Lake City | Utah | 84112 | Recruiting |
| NEXT Oncology Virginia | Fairfax | Virginia | 22031 | Recruiting |
| Fred Hutchinson Cancer Center | Seattle | Washington | 09109 | Recruiting |
| Summit Cancer Centers | Spokane | Washington | 99208 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05377996, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 13, 2026 · Synced Apr 29, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05377996 live on ClinicalTrials.gov.