A Study of ASP3082 in Adults With Advanced Solid Tumors
Public ClinicalTrials.gov record NCT05382559. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1 Study of ASP3082 in Participants With Locally Advanced or Metastatic Solid Tumor Malignancies With KRAS G12D Mutation
Study identification
- NCT ID
- NCT05382559
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- Astellas Pharma Inc
- Industry
- Enrollment
- 681 participants
Conditions and interventions
Conditions
Interventions
- Carboplatin Drug
- Cetuximab Drug
- Cisplatin Drug
- Docetaxel Drug
- Fluorouracil Drug
- Gemcitabine Drug
- Irinotecan Drug
- Leucovorin Drug
- Liposomal Irinotecan Drug
- Nanoparticle albumin-bound-paclitaxel Drug
- Oxaliplatin Drug
- Pembrolizumab Drug
- Pemetrexed Drug
- Setidegrasib Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 7, 2022
- Primary completion
- Dec 30, 2028
- Completion
- Dec 30, 2028
- Last update posted
- Apr 13, 2026
2022 – 2028
United States locations
- U.S. sites
- 23
- U.S. states
- 16
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| City of Hope National Medical Center | Duarte | California | 91010 | Recruiting |
| UCLA Santa Monica Hematology Oncology | Santa Monica | California | 90404 | Recruiting |
| Denver HealthONE Drug Development Unit | Denver | Colorado | 80218 | Recruiting |
| Smilow Cancer Center at Yale New Haven Hospital | New Haven | Connecticut | 06520-8028 | Recruiting |
| Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | Recruiting |
| University of Florida, Davis Cancer Center | Gainesville | Florida | 32610 | Recruiting |
| Florida Cancer Specialist | Lake Mary | Florida | 32746 | Recruiting |
| Florida Cancer Specialists & Research Institute Sarasota | Sarasota | Florida | 34232-6422 | Recruiting |
| University of Kansas Medical Center | Westwood | Kansas | 66205 | Recruiting |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | Recruiting |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02215 | Recruiting |
| Trinity Health Ann Arbor Hospital | Ypsilanti | Michigan | 48197 | Recruiting |
| Washington University School of Medicine | St Louis | Missouri | 63110 | Recruiting |
| Roswell Park Cancer Institute | Buffalo | New York | 14263 | Recruiting |
| Columbia University - Herbert Irving Comprehensive Cancer Center | New York | New York | 10032 | Recruiting |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | Recruiting |
| Case Western | Cleveland | Ohio | 44106 | Recruiting |
| Oregon Health and Science University | Portland | Oregon | 97239 | Recruiting |
| SCRI Oncology Partners | Nashville | Tennessee | 37203 | Terminated |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | Recruiting |
| NEXT Oncology | San Antonio | Texas | 78229 | Recruiting |
| NEXT Oncology - Virginia Cancer Specialists | Fairfax | Virginia | 22031 | Recruiting |
| University of Wisconsin Hospital | Madison | Wisconsin | 53792 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 30 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05382559, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 13, 2026 · Synced May 8, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05382559 live on ClinicalTrials.gov.