PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes
Public ClinicalTrials.gov record NCT05390892. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
PRECIDENTD: PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
PRECIDENTD is a randomized, open label, pragmatic clinical trial designed to compare rates of the total number of cardiovascular, kidney, and death events among two alternative treatments for patients with type 2 diabetes (T2D) and either established atherosclerotic cardiovascular disease (ASCVD) or at high risk for ASCVD. To accomplish this objective, we will randomly assign 6,000 patients with established T2D and ASCVD or high-risk for ASCVD in a 1:1 allocation to sodium-glucose cotransporter-2 inhibitor (SGLT2i) or glucagon-like peptide-1 receptor agonists (GLP-1RA). Participants will be followed for the occurrence of the trial primary endpoint of the total (first and recurrent) number of episodes of myocardial infarction (MI), stroke, arterial revascularization, hospitalization for heart failure, development of end-stage kidney disease, kidney transplantation, and mortality, counting all events from randomization until end of study.
Study identification
- NCT ID
- NCT05390892
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 6,000 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 40 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 25, 2022
- Primary completion
- Feb 28, 2029
- Completion
- Feb 28, 2029
- Last update posted
- Apr 12, 2026
2022 – 2029
United States locations
- U.S. sites
- 36
- U.S. states
- 25
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Longwood Research LLC | Huntsville | Alabama | 35801 | Recruiting |
| HonorHealth Research & Innovation Institute | Scottsdale | Arizona | 85258 | Recruiting |
| Eastside Clinical Research Associates | Los Angeles | California | 90022 | Recruiting |
| Kendall South Medical Center, Inc | Miami | Florida | 33185 | Recruiting |
| South Florida Research Solutions, LLC | Pembroke Pines | Florida | 33028 | Recruiting |
| NSC Research, Inc. | Johns Creek | Georgia | 30024 | Recruiting |
| Herman Clinical Research | Suwanee | Georgia | 30024 | Recruiting |
| University of Illinois Chicago | Chicago | Illinois | 60612 | Recruiting |
| Rush University Medical Center | Hinsdale | Illinois | 60521 | Recruiting |
| University of Iowa | Iowa City | Iowa | 52242 | Recruiting |
| University of Kansas Medical Center | Fairway | Kansas | 66205 | Recruiting |
| Johns Hopkins School of Medicine | Baltimore | Maryland | 21205 | Recruiting |
| MedStar Union Memorial Hospital | Baltimore | Maryland | 21218 | Recruiting |
| MedStar Health Research Institute - Good Samaritan Hospital | Baltimore | Maryland | 21239 | Recruiting |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | Recruiting |
| UMass Chan Medical School | Worcester | Massachusetts | 01655 | Recruiting |
| University of Michigan | Ann Arbor | Michigan | 48109 | Recruiting |
| Essentia Health | Duluth | Minnesota | 55805 | Recruiting |
| University of Minnesota | Minneapolis | Minnesota | 55455 | Recruiting |
| University of Missouri-Columbia | Columbia | Missouri | 65212 | Recruiting |
| University of Nebraska Medical Center | Omaha | Nebraska | 68198 | Recruiting |
| Naomi Berrie Diabetes Center at New York Presbyterian-Columbia University | New York | New York | 10032 | Recruiting |
| Atrium Health Family Medicine Research Department | Charlotte | North Carolina | 28207 | Recruiting |
| Duke University Hospital | Durham | North Carolina | 27710 | Recruiting |
| Wooster Heart Group | Wooster | Ohio | 44691 | Recruiting |
| Oregon Health & Science University | Portland | Oregon | 97239 | Recruiting |
| Geisinger Medical Center | Danville | Pennsylvania | 17821 | Recruiting |
| Temple University Lewis Katz School of Medicine | Philadelphia | Pennsylvania | 19140 | Recruiting |
| Family Care Center at Kent Hospital | Pawtucket | Rhode Island | 02860 | Recruiting |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | Recruiting |
| South Carolina Clinical Research, LLC | Orangeburg | South Carolina | 29118 | Recruiting |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | Recruiting |
| Premier Internal Medicine Associates of Houston | Katy | Texas | 77493 | Recruiting |
| North Dallas Research Associates | McKinney | Texas | 75069 | Recruiting |
| Kidney and Hypertension Specialists, PLLC | Manassas | Virginia | 20110 | Recruiting |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05390892, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 12, 2026 · Synced Sep 1, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05390892 live on ClinicalTrials.gov.