A Research Study to See How Well CagriSema Helps People With Type 2 Diabetes and Excess Body Weight Lose Weight
Public ClinicalTrials.gov record NCT05394519. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Efficacy and Safety of Cagrilintide s.c. 2.4 mg in Combination With Semaglutide s.c. 2.4 mg (CagriSema s.c. 2.4 mg/2.4 mg) Once-weekly in Participants With Overweight or Obesity and Type 2 Diabetes
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will look at how well the new medicine CagriSema helps people living with excess body weight and type 2 diabetes losing weight. Participants will either get CagriSema or a dummy medicine. Which treatment they get is decided by chance. The study will last for about 1½ years. Women cannot take part if pregnant, breast-feeding or planning to get pregnant during the study period.
Study identification
- NCT ID
- NCT05394519
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,200 participants
Conditions and interventions
Conditions
Interventions
- Cagrilintide Drug
- Semaglutide Drug
- Placebo cagrilintide Drug
- Placebo semaglutide Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 1, 2023 (Actual)
- Primary completion
- Jan 28, 2025 (Actual)
- Completion
- Feb 3, 2025 (Actual)
- Last update posted
- Jan 28, 2026
2023 – 2025
United States locations
- U.S. sites
- 49
- U.S. states
- 22
- U.S. cities
- 42
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| John Muir Physicians Network | Concord | California | 94520 | — |
| Headlands Research California, LLC | Escondido | California | 92025 | — |
| Providence Medical Foundation | Fullerton | California | 92835 | — |
| St. Jos Heritage Hlthcr_Fllrtn | Fullerton | California | 92835 | — |
| Diabetes/Lipid Mgmt & Res Ctr | Huntington Beach | California | 92648 | — |
| Clinical Trials Research | Lincoln | California | 95648 | — |
| Velocity Clin Res Los Angeles | Los Angeles | California | 90017 | — |
| Velocity Clin Res Wstlke | Los Angeles | California | 90057 | — |
| Desert Oasis Hlthcr Med Group | Palm Springs | California | 92262 | — |
| Diablo Clinical Research, Inc. | Walnut Creek | California | 94598 | — |
| New West Physicians,Inc. | Golden | Colorado | 80401 | — |
| Clinical Res Of W Florida Inc | Clearwater | Florida | 33765 | — |
| Northeast Research Institute | Fleming Island | Florida | 32003 | — |
| Jacksonville Ctr For Clin Res | Jacksonville | Florida | 32216 | — |
| Renstar Medical Research | Ocala | Florida | 34470 | — |
| AdventHealth Diab Inst | Orlando | Florida | 32804 | — |
| Florida Institute for Clinical Research, LLC | Orlando | Florida | 32825 | — |
| Oviedo Medical Research, LLC | Oviedo | Florida | 32765 | — |
| Endo Res Solutions Inc | Roswell | Georgia | 30076 | — |
| East West Med Res Inst | Honolulu | Hawaii | 96814 | — |
| Cedar-Crosse Research Center | Chicago | Illinois | 60607 | — |
| Iowa Diab & Endo Res Center | West Des Moines | Iowa | 50266 | — |
| Cotton-Oneill Diabetes and End | Topeka | Kansas | 66606-2806 | — |
| L-MARC Research Center | Louisville | Kentucky | 40213 | — |
| Pennington Biom Res Ctr | Baton Rouge | Louisiana | 70808 | — |
| Northern Pines Hlth Ctr, PC | Buckley | Michigan | 49620 | — |
| International Diabetes Center | Minneapolis | Minnesota | 55416 | — |
| StudyMetrix Research LLC | City of Saint Peters | Missouri | 63303 | — |
| Mercury Str Med Grp, PLLC | Butte | Montana | 59701 | — |
| AMC Community Endocrinology | Albany | New York | 12203 | — |
| Southgate Medical Group, LLP | West Seneca | New York | 14224 | — |
| Great Lakes Medical Research | Westfield | New York | 14787 | — |
| PharmQuest Life Sciences LLC | Greensboro | North Carolina | 27408 | — |
| Hillcrest Clinical Research | Simpsonville | South Carolina | 29681-1538 | — |
| Holston Medical Group | Kingsport | Tennessee | 37660 | — |
| Amarillo Med Spec LLP | Amarillo | Texas | 79106 | — |
| Texas Diab & Endo, P.A. | Austin | Texas | 78731 | — |
| Texas Diab & Endo, P.A. | Austin | Texas | 78749 | — |
| Velocity Clinical Res-Dallas | Dallas | Texas | 75230 | — |
| North Texas Endocrine Center | Dallas | Texas | 75231 | — |
| UT Southwestern Med Cntr | Dallas | Texas | 75390-9302 | — |
| PlanIt Research, PLLC | Houston | Texas | 77079 | — |
| DCOL Ctr for Clin Res | Longview | Texas | 75605 | — |
| Consano Clinical Research, LLC | Shavano Park | Texas | 78231 | — |
| Chrysalis Clinical Research | St. George | Utah | 84790 | — |
| National Clin Res Inc. | Richmond | Virginia | 23294 | — |
| Selma Medical Associates | Winchester | Virginia | 22601-3834 | — |
| Amherst Family Practice P.C. | Winchester | Virginia | 22601 | — |
| Capital Clin Res Ctr,LLC | Olympia | Washington | 98502 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 130 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05394519, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 28, 2026 · Synced Oct 24, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05394519 live on ClinicalTrials.gov.