ClinicalTrials.gov record
Completed Phase 1 Interventional Accepts healthy volunteers

A Safety and Immunogenicity of Intranasal Nanoemulsion Adjuvanted Recombinant Pandemic Flu Vaccine in Healthy Adults

ClinicalTrials.gov ID: NCT05397119

Public ClinicalTrials.gov record NCT05397119. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 20, 2026, 8:47 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Ph1 Randomized Double-Blind Controlled Dose-Range Safety Tolerability & Immunogenicity Study of 2 Doses of Intranasal rH5 Flu Vaccine With & Without Nanoemulsion Adjuvant Followed by 1 Boost of Intramuscular H5N1 Vaccine in Healthy Adults

Study identification

NCT ID
NCT05397119
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
BlueWillow Biologics
Industry
Enrollment
40 participants

Conditions and interventions

Interventions

  • BW-1014: 100 µg rH5 in 20% NE - pipette - IN Biological
  • BW-1014: 25 µg rH5 in 20% NE - pipette - IN Biological
  • BW-1014: 50 µg rH5 in 20% NE - pipette - IN Biological
  • H5N1 IIV - IM Biological
  • Saline (Placebo) - pipette - IN Biological
  • rH5 (100 µg) control - pipette - IN Biological

Biological

Eligibility (public fields only)

Age range
18 Years to 45 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 6, 2022
Primary completion
Oct 11, 2023
Completion
Oct 11, 2023
Last update posted
Aug 21, 2024

2022 – 2023

United States locations

U.S. sites
1
U.S. states
1
U.S. cities
1
Facility City State ZIP Site status
Center for Vaccine Development and Global Health, University of Maryland School of Medicine Baltimore Maryland 21201

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05397119, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 21, 2024 · Synced May 20, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05397119 live on ClinicalTrials.gov.

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