A Study to Learn About the Safety of BIIB080 Injections and Whether They Can Improve Symptoms of Participants With Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD Dementia Between 50 to 80 Years of Age
Public ClinicalTrials.gov record NCT05399888. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Assess the Efficacy, Safety, and Tolerability of BIIB080 in Subjects With Mild Cognitive Impairment Due to Alzheimer's Disease or Mild Alzheimer's Disease Dementia
Study identification
- NCT ID
- NCT05399888
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Biogen
- Industry
- Enrollment
- 416 participants
Conditions and interventions
Interventions
- BIIB080 Drug
- BIIB080-matching placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 50 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Not listed
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 23, 2022
- Primary completion
- May 13, 2026
- Completion
- Jan 7, 2029
- Last update posted
- May 17, 2025
2022 – 2029
United States locations
- U.S. sites
- 36
- U.S. states
- 13
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Xenoscience Inc. | Phoenix | Arizona | 85004 | — |
| HonorHealth Neurology | Scottsdale | Arizona | 85251 | — |
| Banner Sun Health Research Institute | Sun City | Arizona | 85351 | — |
| Center for Neurosciences | Tucson | Arizona | 85718 | — |
| Mary S. Easton Center for Alzheimer's Disease Research, UCLA | Los Angeles | California | 90095 | — |
| PNS Clinical Research, LLC dba | Orange | California | 92868 | — |
| Stanford Hospital and Clinics | Palo Alto | California | 94304 | — |
| Sutter Institute for Medical Research | Sacramento | California | 95816 | — |
| University of California San Diego Medical Center | San Diego | California | 92103 | — |
| University of California San Francisco (PARENT) | San Francisco | California | 94143 | — |
| Rocky Mountain Movement Disorders Center, PC | Englewood | Colorado | 80113 | — |
| Charter Research, LLC | Lady Lake | Florida | 32159 | — |
| K2 Medical Research, LLC | Orlando | Florida | 32751 | — |
| Advent Health | Orlando | Florida | 32804 | — |
| Conquest Research | Winter Park | Florida | 32789 | — |
| Charter Research, LLC | Winter Park | Florida | 32792 | — |
| Hawaii Pacific Neuroscience | Honolulu | Hawaii | 96817 | — |
| Brigham and Women's Hospital Department of Neurology | Boston | Massachusetts | 02115-5804 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02216 | — |
| Lahey Clinic Medical Center - Burlington | Burlington | Massachusetts | 01805 | — |
| Boston Center for Memory | Newton | Massachusetts | 02459 | — |
| Neurological Associates of Albany, PC | Albany | New York | 12208 | — |
| Dent Neurologic Institute | Amherst | New York | 14226 | — |
| New York University Medical Center PRIME | New York | New York | 10016 | — |
| South Shore Neurologic Associates, P.C. | Patchogue | New York | 11772 | — |
| SUNY Upstate Medical University | Syracuse | New York | 13210 | — |
| Duke University | Durham | North Carolina | 27710 | — |
| AMC Research, LLC | Matthews | North Carolina | 28105 | — |
| NeuroScience Research Center, LLC. | Canton | Ohio | 44718 | — |
| University of Cincinnati Physicians Group, LLC | Cincinnati | Ohio | 45206-0829 | — |
| Butler Hospital | Providence | Rhode Island | 02906 | — |
| Neurology Clinic, PC | Cordova | Tennessee | 38018 | — |
| Neurology Consultants of Dallas, PA | Dallas | Texas | 75243 | — |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229 | — |
| EvergreenHealth | Kirkland | Washington | 98034 | — |
| Kingfisher Cooperative, LLC | Spokane | Washington | 99202 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 102 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05399888, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 17, 2025 · Synced Apr 20, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05399888 live on ClinicalTrials.gov.