Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Follicular Lymphoma
Public ClinicalTrials.gov record NCT05409066. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Open-Label Study to Evaluate Safety and Efficacy of Epcoritamab in Combination With Rituximab and Lenalidomide (R2) Compared to R2 in Subjects With Relapsed or Refractory Follicular Lymphoma (EPCORE FL-1)
Study identification
- NCT ID
- NCT05409066
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Genmab
- Industry
- Enrollment
- 549 participants
Conditions and interventions
Conditions
Interventions
- Epcoritamab Drug
- Lenalidomide Drug
- Rituximab Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 19, 2022
- Primary completion
- Nov 30, 2029
- Completion
- Nov 30, 2029
- Last update posted
- Jul 27, 2025
2022 – 2029
United States locations
- U.S. sites
- 31
- U.S. states
- 20
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The University of Arizona Cancer Center - North Campus /ID# 228862 | Tucson | Arizona | 85719 | — |
| University of Arkansas for Medical Sciences /ID# 227198 | Little Rock | Arkansas | 72205 | — |
| Alta Bates Summit Medical Center for Research /ID# 229428 | Berkeley | California | 94705 | — |
| Beverly Hills Cancer Center /ID# 231535 | Beverly Hills | California | 90211 | — |
| Long Beach Memorial Medical Ct /ID# 228997 | Long Beach | California | 90806-1701 | — |
| University of Southern California /ID# 227195 | Los Angeles | California | 90033 | — |
| Valkyrie Clinical Trials /ID# 268502 | Los Angeles | California | 90067 | — |
| Duplicate_Emory University /ID# 227299 | Atlanta | Georgia | 30322-1013 | — |
| Hawaii Cancer Care - Waterfront Plaza /ID# 262448 | Honolulu | Hawaii | 96813-4920 | — |
| Northwestern University Feinberg School of Medicine /ID# 227248 | Chicago | Illinois | 60611-2927 | — |
| Goshen Center for Cancer Care /ID# 227189 | Goshen | Indiana | 46526 | — |
| Community Health Network, Inc. /ID# 259756 | Indianapolis | Indiana | 46250-2042 | — |
| Our Lady Of The Lake Regional Medical Center /ID# 251393 | Baton Rouge | Louisiana | 70808 | — |
| University of Maryland, Baltimore /ID# 227191 | Baltimore | Maryland | 21201 | — |
| Massachusetts General Hospital /ID# 245233 | Boston | Massachusetts | 02114 | — |
| UMass Memorial Medical Center /ID# 227323 | Worcester | Massachusetts | 01605 | — |
| Henry Ford Hospital /ID# 227250 | Detroit | Michigan | 48202 | — |
| St. Luke's Hospital - Chesterfield /ID# 247817 | Chesterfield | Missouri | 63017 | — |
| Intermountain Health St. Vincent Regional Hospital - Cancer Centers of Montana /ID# 251220 | Billings | Montana | 59102 | — |
| Morristown Medical Center /ID# 231427 | Morristown | New Jersey | 07960-6136 | — |
| Roswell Park Cancer Institute /ID# 239128 | Buffalo | New York | 14263 | — |
| NYU Langone Hospital - Long Island /ID# 253343 | Mineola | New York | 11501 | — |
| NYU Laura and Isaac Perlmutter Cancer Center /ID# 227322 | New York | New York | 10016 | — |
| Icahn School of Medicine at Mount Sinai /ID# 227181 | New York | New York | 10029 | — |
| Memorial Sloan Kettering Cancer Center-Koch Center /ID# 227193 | New York | New York | 10065-6007 | — |
| East Carolina University - Brody School of Medicine /ID# 227192 | Greenville | North Carolina | 27834 | — |
| University of Oklahoma, Stephenson Cancer Center /ID# 227325 | Oklahoma City | Oklahoma | 73104-5418 | — |
| Baylor Sammons Cancer Center /ID# 261584 | Dallas | Texas | 75246 | — |
| Texas Oncology - Northeast Texas /ID# 265890 | Tyler | Texas | 75702 | — |
| Intermountain Healthcare LDS Hospital /ID# 259948 | Salt Lake City | Utah | 84143 | — |
| Virginia Commonwealth University Medical Center Main Hospital /ID# 227211 | Richmond | Virginia | 23219 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 242 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05409066, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 27, 2025 · Synced May 9, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05409066 live on ClinicalTrials.gov.