Study of ORIC-944 in Patients With Metastatic Prostate Cancer
Public ClinicalTrials.gov record NCT05413421. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-Label, Phase 1/1b Study of ORIC-944 as a Single Agent or in Combination With an Androgen Receptor Pathway Inhibitor in Patients With Metastatic Prostate Cancer
Study identification
- NCT ID
- NCT05413421
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- ORIC Pharmaceuticals
- Industry
- Enrollment
- 250 participants
Conditions and interventions
Conditions
Interventions
- Abiraterone acetate (Zytiga®) 250 mg or 500 mg tablets Drug
- Apalutamide (Erleada™) 60 mg or 240 mg tablets Drug
- Darolutamide (Nubeqa®) 300 mg tablets Drug
- Enzalutamide (Xtandi®) 40 mg capsules or 40 mg and 80 mg tablets Drug
- ORIC-944 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Male
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 31, 2022
- Primary completion
- Nov 30, 2025
- Completion
- Aug 31, 2026
- Last update posted
- Aug 10, 2025
2022 – 2026
United States locations
- U.S. sites
- 20
- U.S. states
- 15
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Rocky Mountain Cancer Center | Colorado Springs | Colorado | 80907 | Recruiting |
| South Florida Oncology and Hematology | Plantation | Florida | 33322 | Recruiting |
| Illinois Cancer Specialists | Arlington Heights | Illinois | 60005 | Recruiting |
| Comprehensive Urologic Care | Lake Barrington | Illinois | 60010 | Recruiting |
| First Urology | Jeffersonville | Indiana | 47130 | Recruiting |
| Marlene & Stewart Greenebaum Comprehensive Cancer Center, University of Maryland | Baltimore | Maryland | 21201 | Recruiting |
| Maryland Oncology Hematology | Silver Spring | Maryland | 20904 | Recruiting |
| Karmanos | Detroit | Michigan | 48201 | Recruiting |
| Minnesota Oncology Hematology | Minneapolis | Minnesota | 55404 | Recruiting |
| Memorial Sloane Kettering Cancer Center | New York | New York | 10065 | Recruiting |
| Levine Cancer Institute | Charlotte | North Carolina | 28204 | Recruiting |
| MidLantic Urology | Bala-Cynwyd | Pennsylvania | 19004 | Not yet recruiting |
| Keystone Urology Specialists | Lancaster | Pennsylvania | 17601 | Recruiting |
| Amarillo Urology Research | Amarillo | Texas | 74035 | Recruiting |
| Urology Clinics of North Texas | Dallas | Texas | 75231 | Recruiting |
| Huntsman Cancer Institute, University of Utah | Salt Lake City | Utah | 84112 | Recruiting |
| Virginia Oncology Associates | Fairfax | Virginia | 22031 | Recruiting |
| Virginia Cancer Specialists | Norfolk | Virginia | 23502 | Not yet recruiting |
| University of Washington, Fred Hutchinson Cancer Center | Seattle | Washington | 98109 | Recruiting |
| University of Wisconsin Carbone Cancer Center | Madison | Wisconsin | 53792 | Not yet recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05413421, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 10, 2025 · Synced May 6, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05413421 live on ClinicalTrials.gov.