Study of Emactuzumab for Tenosynovial Giant Cell Tumor (TGCT)
Public ClinicalTrials.gov record NCT05417789. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Multicentre, Randomised, Double-Blind Study to Assess the Safety and Efficacy of Emactuzumab vs. Placebo in Subjects With Tenosynovial Giant Cell Tumour
Study identification
- NCT ID
- NCT05417789
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- SynOx Therapeutics Limited
- Industry
- Enrollment
- 128 participants
Conditions and interventions
Conditions
Interventions
- Emactuzumab Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 8, 2024
- Primary completion
- Dec 22, 2025
- Completion
- Sep 29, 2027
- Last update posted
- Feb 1, 2026
2024 – 2027
United States locations
- U.S. sites
- 10
- U.S. states
- 8
- U.S. cities
- 9
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| NextGen Oncology | Beverly Hills | California | 90212 | — |
| Sarcoma Oncology Research Center, LLC | Los Angeles | California | 90067 | — |
| USC Norris Comprehensive Cancer Center | Los Angeles | California | 90089 | — |
| University of Kansas Cancer Center (Overland Park) - USOR | Overland Park | Kansas | 66210 | — |
| University of Minnesota | Minneapolis | Minnesota | 55455 | — |
| Duke Cancer Center | Durham | North Carolina | 27710 | — |
| The Ohio State University | Columbus | Ohio | 43201 | — |
| OHSU Knight Cancer Institute Hematology Oncology | Portland | Oregon | 97239 | — |
| MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| MedStar Washington Hospital Center | Georgetown | Washington | 20010 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 38 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05417789, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 1, 2026 · Synced May 18, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05417789 live on ClinicalTrials.gov.