A Study of JNJ-90014496 in Participants With B-Cell Non-Hodgkin Lymphoma

ClinicalTrials.gov ID: NCT05421663

Public ClinicalTrials.gov record NCT05421663. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Apr 24, 2026, 1:45 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1b/2, Multicenter, Open-label, Study of JNJ-90014496, an Autologous CD19/CD20 Bi-specific CAR-T Cell Therapy in Adult Participants With B-cell Non-Hodgkin Lymphoma

Study identification

NCT ID: NCT05421663
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 1, Phase 2
Lead sponsor: Janssen Research & Development, LLC; Industry
Enrollment: 439 participants

Conditions and interventions

Conditions

Interventions

Prizloncabtagene autoleucel (Prizlo-Cel) Biological

Biological

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Aug 11, 2022
Primary completion: Dec 28, 2028
Completion: Mar 28, 2029
Last update posted: Apr 12, 2026

2022 – 2029

United States locations

U.S. sites: 14
U.S. states: 11
U.S. cities: 13

Facility	City	State	ZIP	Site status
City of Hope	Duarte	California	91010	Recruiting
Colorado Blood Cancer Institute	Denver	Colorado	80218	Recruiting
University of Iowa Hospital and Clinics	Iowa City	Iowa	52242	Recruiting
University of Kentucky Medical Center	Lexington	Kentucky	40536	Recruiting
Rutgers Cancer Institute of New Jersey	Piscataway	New Jersey	08854	Recruiting
Levine Cancer Institute	Charlotte	North Carolina	28001	Recruiting
University Hospitals Cleveland Medical Center	Cleveland	Ohio	44106	Recruiting
University of Pittsburgh Medical Center	Pittsburgh	Pennsylvania	15232	Recruiting
Greco Hainesworth Tennessee Oncology Centers for Research	Nashville	Tennessee	37203	Recruiting
Sarah Cannon Research Institute	Nashville	Tennessee	37203	Recruiting
St. David's South Austin Medical Center	Austin	Texas	78704	Recruiting
MD Anderson Cancer Center	Houston	Texas	77030	Recruiting
Texas Transplant Institute	San Antonio	Texas	78229	Recruiting
Swedish Cancer Institute	Seattle	Washington	98104	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 18 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT05421663, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 12, 2026 · Synced Apr 24, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05421663 live on ClinicalTrials.gov.

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