SPECT-CT Guided ELEctive Contralateral Neck Treatment for Patients With Lateralized Oropharyngeal Cancer
Public ClinicalTrials.gov record NCT05451004. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
SPECT-CT Guided ELEctive Contralateral Neck Treatment for Patients With Lateralized Oropharyngeal Cancer. A Phase III Randomized Controlled Trial
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is being done to answer the following question: Is the chance of cancer spreading or returning the same if radiotherapy to the neck is guided, by using a special imaging study called lymph node mapping (lymphatic mapping) Single Photon Emission Computed Tomography (SPECT-CT), compared to the usual treatment when radiotherapy is given to both sides of the neck?
Study identification
- NCT ID
- NCT05451004
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 510 participants
Conditions and interventions
Conditions
Interventions
- Lymphatic Mapping with SPECT-CT Other
- Ipsilateral and Contralateral Neck Radiation
Other · Radiation
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 9, 2023
- Primary completion
- Aug 29, 2030
- Completion
- Aug 29, 2031
- Last update posted
- Jul 13, 2026
2023 – 2031
United States locations
- U.S. sites
- 28
- U.S. states
- 12
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| City of Hope Corona | Corona | California | 92882 | Recruiting |
| City of Hope Comprehensive Cancer Center | Duarte | California | 91010 | Recruiting |
| City of Hope at Irvine Lennar | Irvine | California | 92618 | Suspended |
| UM Sylvester Comprehensive Cancer Center at Coral Gables | Coral Gables | Florida | 33146 | Recruiting |
| Baptist MD Anderson Cancer Center | Jacksonville | Florida | 32207 | Active, not recruiting |
| University of Miami Miller School of Medicine-Sylvester Cancer Center | Miami | Florida | 33136 | Recruiting |
| Moffitt Cancer Center-International Plaza | Tampa | Florida | 33607 | Recruiting |
| Moffitt Cancer Center - McKinley Campus | Tampa | Florida | 33612 | Recruiting |
| Moffitt Cancer Center | Tampa | Florida | 33612 | Recruiting |
| Emory University Hospital Midtown | Atlanta | Georgia | 30308 | Recruiting |
| Northwestern University | Chicago | Illinois | 60611 | Active, not recruiting |
| Northwestern Medicine Cancer Center Warrenville | Warrenville | Illinois | 60555 | Active, not recruiting |
| The James Graham Brown Cancer Center at University of Louisville | Louisville | Kentucky | 40202 | Suspended |
| University of Michigan Rogel Cancer Center | Ann Arbor | Michigan | 48109 | Recruiting |
| University of Michigan - Brighton Center for Specialty Care | Brighton | Michigan | 48116 | Recruiting |
| Henry Ford Hospital | Detroit | Michigan | 48202 | Recruiting |
| MU Health - University Hospital/Ellis Fischel Cancer Center | Columbia | Missouri | 65212 | Recruiting |
| UNC Lineberger Comprehensive Cancer Center | Chapel Hill | North Carolina | 27599 | Recruiting |
| MetroHealth Medical Center | Cleveland | Ohio | 44109 | Recruiting |
| Providence Portland Medical Center | Portland | Oregon | 97213 | Recruiting |
| UT MD Anderson - The Woodlands | Conroe | Texas | 77384 | Recruiting |
| UT MD Anderson Cancer Center | Houston | Texas | 77030 | Recruiting |
| UT MD Anderson - West Houston | Houston | Texas | 77079 | Recruiting |
| UT MD Anderson - League City | League City | Texas | 77573 | Recruiting |
| UT MD Anderson - Sugar Land | Sugar Land | Texas | 77478 | Recruiting |
| Central Vermont Medical Center/National Life Cancer Treatment | Berlin Corners | Vermont | 05602 | Recruiting |
| University of Vermont Medical Center | Burlington | Vermont | 05401 | Recruiting |
| University of Vermont and State Agricultural College | Burlington | Vermont | 05405 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 10 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05451004, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 13, 2026 · Synced Sep 10, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05451004 live on ClinicalTrials.gov.