ClinicalTrials.gov record
Recruiting Phase 1 Interventional

A First-in-human Study of IBI343 in Subjects With Locally Advanced Unresectable or Metastatic Solid Tumors

ClinicalTrials.gov ID: NCT05458219

Public ClinicalTrials.gov record NCT05458219. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 8, 2026, 6:33 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1a/b, Multicenter, Open-label, First-in-human Study of IBI343 in Subjects With Locally Advanced Unresectable or Metastatic Solid Tumors

Study identification

NCT ID
NCT05458219
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 1
Lead sponsor
Innovent Biologics (Suzhou) Co. Ltd.
Industry
Enrollment
470 participants

Conditions and interventions

Interventions

  • FOLFIRINOX/mFOLFIRINOX Drug
  • IBI343 Drug
  • mFOLFOX Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 25, 2022
Primary completion
Jun 29, 2027
Completion
Dec 30, 2027
Last update posted
May 3, 2026

2022 – 2027

United States locations

U.S. sites
3
U.S. states
1
U.S. cities
3
Facility City State ZIP Site status
Next Oncology-Austin Austin Texas 78758 Recruiting
Next Oncology-Dallas Irving Texas 75039 Recruiting
Next Oncology-San Antonio San Antonio Texas 78229 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 36 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05458219, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 3, 2026 · Synced May 8, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05458219 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →