A Study of Remternetug (LY3372993) in Participants With Alzheimer's Disease (TRAILRUNNER-ALZ 1)
Public ClinicalTrials.gov record NCT05463731. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Assessment of Safety, Tolerability, and Efficacy Measured by Amyloid Reduction of LY3372993 in Early Symptomatic Alzheimer's Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The reason for this study is to collect safety and efficacy information regarding the study drug remternetug in participants with early symptomatic Alzheimer's disease (AD).
Study identification
- NCT ID
- NCT05463731
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,667 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 60 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 1, 2022 (Actual)
- Primary completion
- Apr 24, 2024 (Actual)
- Completion
- May 12, 2026 (Actual)
- Last update posted
- May 22, 2026
2022 – 2026
United States locations
- U.S. sites
- 73
- U.S. states
- 24
- U.S. cities
- 69
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| MD First Research - Chandler | Chandler | Arizona | 85286 | — |
| Hope Clinical Research, Inc. | Canoga Park | California | 91303 | — |
| North County Neurology Associates | Carlsbad | California | 92011 | — |
| Wr- Pri, Llc | Encino | California | 91316 | — |
| Neuro-Pain Medical Center | Fresno | California | 93710 | — |
| Irvine Clinical Research | Irvine | California | 92614 | — |
| Kaizen Brain Center | La Jolla | California | 92037 | — |
| Anderson Clinical Research | Redlands | California | 92374 | — |
| Mountain Neurological Research Center | Basalt | Colorado | 81621 | — |
| Alpine Clinical Research Center | Boulder | Colorado | 80301 | — |
| Colorado Springs Neurological Associates | Colorado Springs | Colorado | 80907 | — |
| Institute for Neurodegenerative Disorders | New Haven | Connecticut | 06510 | — |
| Ki Health Partners, LLc, dba New England Institute for Clinical Research | Stamford | Connecticut | 06905 | — |
| JEM Research Institute | Atlantis | Florida | 33462 | — |
| VIN-Julie Schwartzbard | Aventura | Florida | 33180 | — |
| Brain Matters Research | Delray Beach | Florida | 33445 | — |
| Neuropsychiatric Research Center of Southwest Florida | Fort Myers | Florida | 33912 | — |
| Finlay Medical Research | Greenacres City | Florida | 33467 | — |
| Encore Research Group- Jacksonville Center for Clinical Research | Jacksonville | Florida | 32216 | — |
| ClinCloud - Maitland | Maitland | Florida | 32751 | — |
| K2 Medical Research | Maitland | Florida | 32751 | — |
| ClinCloud - Viera | Melbourne | Florida | 32940 | — |
| Merritt Island Medical Research, LLC | Merritt Island | Florida | 32952 | — |
| VIN-Andrew Lerman | Miami | Florida | 33133 | — |
| Optimus U Corporation | Miami | Florida | 33135 | — |
| Suncoast Clinical Research, Inc. | New Port Richey | Florida | 34652 | — |
| Renstar Medical Research | Ocala | Florida | 34470 | — |
| Charter Research - Winter Park | Orlando | Florida | 32803 | — |
| Emerald Coast Neurology - Airport Boulevard | Pensacola | Florida | 32504 | — |
| Progressive Medical Research | Port Orange | Florida | 32127 | — |
| Alzheimer's Research and Treatment Center | Stuart | Florida | 34997 | — |
| Brain Matters Research | Stuart | Florida | 34997 | — |
| Tallahassee Neurological Clinic | Tallahassee | Florida | 32308 | — |
| Charter Research - Lady Lake | The Villages | Florida | 32162 | — |
| Alzheimer's Research and Treatment Center | Wellington | Florida | 33414 | — |
| Palm Beach Neurology | West Palm Beach | Florida | 33407 | — |
| Conquest Research | Winter Park | Florida | 32789 | — |
| Columbus Memory Center, PC | Columbus | Georgia | 31909 | — |
| iResearch Atlanta | Decatur | Georgia | 30030 | — |
| Great Lakes Clinical Trials - Andersonville | Chicago | Illinois | 60640 | — |
| AMITA Health - Alexian Brothers Neurosciences Institute Clinical Research | Elk Grove Village | Illinois | 60007 | — |
| Covenant Medical Center | Waterloo | Iowa | 50702 | — |
| Cotton O'Neil Clinical Research Center - Central Office | Topeka | Kansas | 66606 | — |
| Care Access - Lake Charles | Lake Charles | Louisiana | 70601 | — |
| MedVadis Research Corporation | Waltham | Massachusetts | 02451 | — |
| Adams Clinical | Watertown | Massachusetts | 02472 | — |
| Citizens Memorial Hospital District | Bolivar | Missouri | 65613 | — |
| Clinical Research Professionals | Chesterfield | Missouri | 63005 | — |
| Las Vegas Medical Research | Las Vegas | Nevada | 89128 | — |
| The Cognitive and Research Center of New Jersey | Springfield | New Jersey | 07081 | — |
| Advanced Memory Research Institute of New Jersey | Toms River | New Jersey | 08755 | — |
| Neurological Associates Albany | Albany | New York | 12208 | — |
| AMC Research | Matthews | North Carolina | 28105 | — |
| Carteret Medical Group | Morehead City | North Carolina | 28557 | — |
| NeuroScience Research Center | Canton | Ohio | 44718 | — |
| Valley Medical Research | Centerville | Ohio | 45459 | — |
| Neurology Diagnostics, Inc. | Dayton | Ohio | 45459 | — |
| Center for Cognitive Health | Portland | Oregon | 97225 | — |
| The Clinical Trial Center, LLC | Jenkintown | Pennsylvania | 19046 | — |
| Keystone Clinical Studies | Plymouth Meeting | Pennsylvania | 19462 | — |
| Rhode Island Mood & Memory Research Institute | East Providence | Rhode Island | 02914 | — |
| Neurology Clinic, P.C. | Cordova | Tennessee | 38018 | — |
| Texas Diabetes & Endocrinology, P.A. | Austin | Texas | 78749 | — |
| Gadolin Research | Beaumont | Texas | 77702 | — |
| Kerwin Medical Center | Dallas | Texas | 75231 | — |
| Neurology Consultants of Dallas, PA | Dallas | Texas | 75243 | — |
| The University of Texas Health Science Center at Houston | Houston | Texas | 77054 | — |
| Central Texas Neurology Consultants | Round Rock | Texas | 78681 | — |
| Consano Clinical Research, LLC | Shavano Park | Texas | 78231 | — |
| Re:Cognition Health | Fairfax | Virginia | 22031 | — |
| National Clinical Research, Inc | Richmond | Virginia | 23294 | — |
| Northwest Clinical Research Center | Bellevue | Washington | 98007 | — |
| Universal Research Group | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05463731, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 22, 2026 · Synced Oct 25, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05463731 live on ClinicalTrials.gov.