ENACT: A Study of ENX-101 as Adjunctive Treatment in Patients With Focal Seizures
Public ClinicalTrials.gov record NCT05481905. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
The ENACT Trial: A Randomized, Double-blind, Placebo-controlled Adjunctive Treatment Trial to Evaluate the Efficacy and Safety of ENX-101 in Patients With Focal (Partial Onset) Seizures
Study identification
- NCT ID
- NCT05481905
- Recruitment status
- Withdrawn
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Engrail Therapeutics INC
- Industry
- Enrollment
- Not listed
Conditions and interventions
Conditions
Interventions
- ENX-101 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 31, 2022
- Primary completion
- Aug 31, 2024
- Completion
- Nov 30, 2024
- Last update posted
- Jul 5, 2023
2022 – 2024
United States locations
- U.S. sites
- 38
- U.S. states
- 22
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Barrow Neurological Institute | Phoenix | Arizona | 85013 | — |
| University of Arizona | Tucson | Arizona | 85724 | — |
| Rancho Research Institute at Rancho Los Amigos National Rehabilitation Center | Downey | California | 90242 | — |
| University of Colorado | Aurora | Colorado | 80045 | — |
| University of Florida Research Institute of Orlando | Gainesville | Florida | 32611 | — |
| Royal Care Medical Research Corporation | Miami | Florida | 33032 | — |
| University of Miami | Miami | Florida | 33136 | — |
| D&H National Research Centers | Miami | Florida | 33155 | — |
| S&G Research Center Corp. | Miami | Florida | 33155 | — |
| Florida Hospital | Orlando | Florida | 32803 | — |
| Comprehensive Neurology Clinic | Orlando | Florida | 32825 | — |
| Emory University School of Medicine | Atlanta | Georgia | 30322 | — |
| Hawaii Pacific Neuroscience | Honolulu | Hawaii | 96817 | — |
| OSF HealthCare Illinois Neurological Institute | Peoria | Illinois | 61603 | — |
| University of Kansas | Kansas City | Kansas | 66160 | — |
| Saint Joseph Health System | Lexington | Kentucky | 40504 | — |
| Maine Medical Partners Neurology | Scarborough | Maine | 04074 | — |
| University of Maryland Medical Center | Baltimore | Maryland | 21201 | — |
| Mid-Atlantic Epilepsy and Sleep Center | Bethesda | Maryland | 20817 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Oakland University William Beaumont School of Medicine | Farmington Hills | Michigan | 48334 | — |
| SRI International | Plymouth | Michigan | 48170 | — |
| Advanced Clinical Research Center | Bridgeton | Missouri | 63044 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Somnos Clinical Research/Neurology Associates | Lincoln | Nebraska | 68510 | — |
| Northeast Regional Epilepsy Group | Hackensack | New Jersey | 07601 | — |
| Institute of Neurology and Neurosurgery at Saint Barnabas LLC | Livingston | New Jersey | 07039 | — |
| Donald and Barbara Zucker School of Medicine at Hofstra/Northwell | New York | New York | 10016 | — |
| University of Rochester | Rochester | New York | 14618 | — |
| Montefiore Medical Center | The Bronx | New York | 10467 | — |
| Atrium Health | Chapel Hill | North Carolina | 28204 | — |
| Duke University School of Medicine | Durham | North Carolina | 27710 | — |
| NeuroScience Research Center, LLC | Canton | Ohio | 44718 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 42101 | — |
| University of Pittsburgh | Pittsburgh | Pennsylvania | 15213 | — |
| DJL Clinical Research | Rock Hill | South Carolina | 29732 | — |
| Mt. Olympus Medical Research | Sugar Land | Texas | 77479 | — |
| University of Virginia | Charlottesville | Virginia | 22908 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05481905, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 5, 2023 · Synced May 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05481905 live on ClinicalTrials.gov.