A Dose Escalation Study of HBI-2438 in Patients With Solid Tumors Harboring KRAS G12C Mutation
Public ClinicalTrials.gov record NCT05485974. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1, Open Label, Dose Escalation of HBI-2438 in Patients With Advanced Malignant Solid Tumors Harboring KRAS G12C Mutation
Study identification
- NCT ID
- NCT05485974
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- HUYABIO International, LLC.
- Industry
- Enrollment
- 44 participants
Conditions and interventions
Conditions
Interventions
- HBI-2438 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 31, 2022
- Primary completion
- Dec 30, 2026
- Completion
- Dec 30, 2026
- Last update posted
- Sep 23, 2025
2022 – 2026
United States locations
- U.S. sites
- 13
- U.S. states
- 5
- U.S. cities
- 12
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| California Cancer Associates for Research and Excellence, Inc. (cCare) | Encinitas | California | 92024 | — |
| The Oncology Institute of Hope and Innovation | Glendale | California | 91204 | — |
| The Oncology Institute of Hope and Innovation | Long Beach | California | 90805 | — |
| The Oncology Institute of Hope and Innovation | Pasadena | California | 91105 | — |
| California Cancer Associates for Research and Excellence, Inc. (cCare) | San Marcos | California | 92069 | — |
| The Oncology Institute of Hope and Innovation | Santa Ana | California | 92705 | — |
| Sarcoma Oncology | Santa Monica | California | 90403 | — |
| Innovative Clinical Research Institute (ICRI) | Whittier | California | 90603 | — |
| The Oncology Institute of Hope and Innovation | Whittier | California | 90603 | — |
| BRCR Medical Center | Plantation | Florida | 33322 | — |
| Michigan Center of Medical Research | Farmington Hills | Michigan | 48334 | — |
| Alliance for Multispecialty Research, LLC | Kansas City | Missouri | 64114 | — |
| Gabrail Cancer Center | Canton | Ohio | 44718 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05485974, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 23, 2025 · Synced May 8, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05485974 live on ClinicalTrials.gov.