A Study of LBP-EC01 in the Treatment of Acute Uncomplicated UTI Caused by Drug Resistant E. Coli (ELIMINATE Trial)

ClinicalTrials.gov ID: NCT05488340

Public ClinicalTrials.gov record NCT05488340. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 17, 2026, 5:32 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Double-blind, Randomized, Active-controlled Evaluation of the Safety, Tolerability, Pharmacokinetics and Efficacy of LBP-EC01 in the Treatment of Acute Uncomplicated Urinary Tract Infection Caused by Drug Resistant E. Coli

Study identification

NCT ID: NCT05488340
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: Locus Biosciences; Industry
Enrollment: 318 participants

Conditions and interventions

Conditions

Urinary Tract Infections

Interventions

LBP-EC01 Drug
LBP-EC01 0.01x IV Dose Drug
LBP-EC01 0.1 x IV dose Drug
LBP-EC01 IV Infusion Dose Drug
Placebo Drug
TMP/SMX Drug

Drug

Eligibility (public fields only)

Age range: 18 Years to 75 Years
Sex: Female
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jul 12, 2022
Primary completion: May 31, 2026
Completion: Nov 30, 2026
Last update posted: Mar 19, 2026

2022 – 2026

United States locations

U.S. sites: 17
U.S. states: 5
U.S. cities: 16

Facility	City	State	ZIP	Site status
Research Site 138	Fresno	California	93710	Completed
Research Site 131	Lancaster	California	93534	Recruiting
Research Site 123	Los Angeles	California	90027	Recruiting
Research Site 125	Montebello	California	90640	Completed
Research Site 152	Murrieta	California	92563	Recruiting
Research Site 137	San Diego	California	92037	Recruiting
Research Site 126	Tustin	California	92780	Recruiting
Research Site 102	Doral	Florida	33166	Recruiting
Research Site 151	Hialeah	Florida	33013	Recruiting
Research Site 140	Jensen Beach	Florida	34957	Completed
Research Site 103	Miami	Florida	33176	Recruiting
Research Site 149	Miami	Florida	33176	Recruiting
Research Site 153	Ocala	Florida	34473	Recruiting
Research Site 120	Boston	Massachusetts	02115	Completed
Research Site 154	St Louis	Missouri	63141	Recruiting
Research Site 145	Raleigh	North Carolina	27708	Recruiting
Research Site 118	Winston-Salem	North Carolina	27157	Completed

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT05488340, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Mar 19, 2026 · Synced May 17, 2026

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The complete protocol, eligibility criteria, and contact information for NCT05488340 live on ClinicalTrials.gov.

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