A Study of CTX-009 in Combination With Paclitaxel in Adult Patients With Unresectable Advanced, Metastatic or Recurrent Biliary Tract Cancers (COMPANION-002)
Public ClinicalTrials.gov record NCT05506943. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2/3 Randomized, Controlled Study of CTX-009 in Combination With Paclitaxel Versus Paclitaxel Alone in Adult Patients With Unresectable Advanced, Metastatic or Recurrent Biliary Tract Cancers Who Have Received One Prior Systemic Chemotherapy Regimen
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a multi-center, open-label, randomized, phase 2/3 trial of the bispecific antibody CTX-009 plus paclitaxel versus paclitaxel in patients with previously treated, unresectable advanced or metastatic biliary tract cancers.
Study identification
- NCT ID
- NCT05506943
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 168 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 9, 2023 (Actual)
- Primary completion
- Aug 31, 2027 (Estimated)
- Completion
- Aug 31, 2027 (Estimated)
- Last update posted
- Sep 2, 2026
2023 – 2027
United States locations
- U.S. sites
- 34
- U.S. states
- 17
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic Arizona | Phoenix | Arizona | 85054 | — |
| University of Arizona | Tucson | Arizona | 85724-5024 | — |
| University of Southern California Norris Comprehensive Cancer Center | Los Angeles | California | 90033 | — |
| Stanford Medicine Cancer Center | Palo Alto | California | 94305 | — |
| University of California San Francisco | San Francisco | California | 94143-1770 | — |
| Rocky Mountain Cancer Centers, LLP | Aurora | Colorado | 80012 | — |
| University of Florida | Gainesville | Florida | 32611 | — |
| Mayo Clinic Jacksonville | Jacksonville | Florida | 32224 | — |
| AdventHealth Orlando | Orlando | Florida | 32804 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| Ochsner Clinic Foundation | New Orleans | Louisiana | 70121 | — |
| Johns Hopkins University | Baltimore | Maryland | 21287 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02141 | — |
| Mayo Clinic Rochester | Rochester | Minnesota | 55905 | — |
| Washington University School of Medicine, Siteman Cancer Center | St Louis | Missouri | 63110 | — |
| Rutgers Cancer Institute | New Brunswick | New Jersey | 08854 | — |
| The University of New Mexico | Albuquerque | New Mexico | 87131 | — |
| Memorial Medical Center | Las Cruces | New Mexico | 88011 | — |
| Roswell Park | Buffalo | New York | 14263 | — |
| Columbia University | New York | New York | 10032 | — |
| Montefiore Medical Center | The Bronx | New York | 10461 | — |
| Gabrail Cancer Center | Canton | Ohio | 44718 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| University of Tennessee Medical Center | Knoxville | Tennessee | 37920 | — |
| SCRI Oncology Partners | Nashville | Tennessee | 37203 | — |
| Texas Oncology - Austin | Austin | Texas | 78705 | — |
| Texas Oncology - Baylor Charles A. Sammons Cancer Center | Dallas | Texas | 75246 | — |
| Texas Oncology - Dension | Denison | Texas | 75020 | — |
| The University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| Texas Oncology - San Antonio | San Antonio | Texas | 78217 | — |
| Texas Oncology - Northeast Texas | Tyler | Texas | 75702 | — |
| Virginia Mason Franciscan Health | Seattle | Washington | 98101 | — |
| Northwest Cancer Specialists, P.C. | Vancouver | Washington | 98684 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05506943, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 2, 2026 · Synced Oct 16, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05506943 live on ClinicalTrials.gov.