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Terminated Phase 1 Interventional

A Study of XMT-2056 in Advanced/Recurrent Solid Tumors That Express HER2

ClinicalTrials.gov ID: NCT05514717

Public ClinicalTrials.gov record NCT05514717. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 23, 2026, 6:21 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1, First-in-Human, Dose Escalation and Expansion, Multicenter Study of XMT-2056 in Participants With Advanced/Recurrent Solid Tumors That Express HER2

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

A Study of XMT-2056 in advanced/recurrent solid tumors that express HER2.

Study identification

NCT ID
NCT05514717
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 1
Enrollment
57 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 24, 2023 (Actual)
Primary completion
May 22, 2026 (Actual)
Completion
May 22, 2026 (Actual)
Last update posted
Jun 18, 2026

2023 – 2026

United States locations

U.S. sites
14
U.S. states
10
U.S. cities
11
Facility City State ZIP Site status
University of South California Los Angeles California 90033 —
University of California Los Angeles Los Angeles California 90095 —
Stanford University Medical Center Stanford California 94305 —
AdventHealth Celebration Celebration Florida 34747 —
Emory Healthcare, Emory Clinic Atlanta Georgia 30322 —
Massachusetts General Hospital Boston Massachusetts 02114 —
Karmanos Cancer Institute Detroit Michigan 48201 —
Hackensack University Medical Center Hackensack New Jersey 07601 —
New York University Medical Oncology Associates New York New York 10016 —
Icahn School of Medicine at Mount Sinai New York New York 10029 —
Memorial Sloan Kettering Cancer Center New York New York 10065 —
The Ohio State University Comprehensive Cancer Center Columbus Ohio 43212 —
Tennessee Oncology, PLLC Nashville Tennessee 37203 —
The University of Texas MD Anderson Cancer Center Houston Texas 77030 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05514717, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 18, 2026 · Synced Oct 23, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT05514717 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →