ClinicalTrials.gov record
A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)
ClinicalTrials.gov ID: NCT05519085
Public ClinicalTrials.gov record NCT05519085. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 6, 2026, 8:54 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Two-Stage, Randomized, Multicenter, Open-Label Study Comparing Mezigdomide (CC-92480), Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Subjects With Relapsed or Refractory Multiple Myeloma (RRMM): SUCCESSOR-1
Study identification
- NCT ID
- NCT05519085
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Celgene
- Industry
- Enrollment
- 810 participants
Conditions and interventions
Conditions
Interventions
- Bortezomib Drug
- Dexamethasone Drug
- Pomalidomide Drug
- mezigdomide Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 19, 2022
- Primary completion
- Jan 9, 2027
- Completion
- Nov 29, 2033
- Last update posted
- Apr 29, 2026
2022 – 2033
United States locations
- U.S. sites
- 56
- U.S. states
- 24
- U.S. cities
- 53
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Local Institution - 0366 | Los Alamitos | California | 90720 | Active, not recruiting |
| Local Institution - 0272 | San Diego | California | 92123 | Completed |
| Local Institution - 0273 | West Hollywood | California | 90069 | Completed |
| Local Institution - 0381 | Aurora | Colorado | 80045 | Not yet recruiting |
| Local Institution - 0380 | Farmington | Connecticut | 06030 | Active, not recruiting |
| Local Institution - 0208 | New Haven | Connecticut | 06510 | Withdrawn |
| Local Institution - 0303 | Coral Springs | Florida | 33321 | Active, not recruiting |
| Local Institution - 0403 | Fort Myers | Florida | 33901 | Active, not recruiting |
| Local Institution - 0401 | St. Petersburg | Florida | 33701 | Active, not recruiting |
| Local Institution - 0402 | West Palm Beach | Florida | 33401 | Active, not recruiting |
| Local Institution - 0211 | Athens | Georgia | 30607 | Active, not recruiting |
| Local Institution - 0048 | Marietta | Georgia | 30060 | Withdrawn |
| Local Institution - 0330 | Garden City | Kansas | 67846 | Completed |
| Local Institution - 0080 | Westwood | Kansas | 66205 | Active, not recruiting |
| Local Institution - 0358 | Baton Rouge | Louisiana | 70808 | Active, not recruiting |
| Local Institution - 0255 | New Orleans | Louisiana | 70112 | Active, not recruiting |
| Local Institution - 0385 | Shreveport | Louisiana | 71103 | Not yet recruiting |
| Local Institution - 0357 | Baltimore | Maryland | 21215 | Active, not recruiting |
| Local Institution - 0246 | Boston | Massachusetts | 02215 | Active, not recruiting |
| Local Institution - 0271 | Ann Arbor | Michigan | 48109 | Active, not recruiting |
| Local Institution - 0364 | Detroit | Michigan | 48202 | Active, not recruiting |
| Local Institution - 0410 | Minneapolis | Minnesota | 55404 | Active, not recruiting |
| Local Institution - 0088 | Hattiesburg | Mississippi | 39401 | Active, not recruiting |
| Local Institution - 0242 | Jackson | Mississippi | 39213 | Withdrawn |
| Local Institution - 0288 | East Brunswick | New Jersey | 08816 | Active, not recruiting |
| Local Institution - 0363 | Ridgewood | New Jersey | 07450 | Not yet recruiting |
| Local Institution - 0302 | Albuquerque | New Mexico | 87131 | Active, not recruiting |
| Local Institution - 0245 | Buffalo | New York | 14215 | Withdrawn |
| Local Institution - 0257 | Lake Success | New York | 11042 | Active, not recruiting |
| Local Institution - 0373 | New Hyde Park | New York | 11042 | Completed |
| Local Institution - 0371 | New York | New York | 10028 | Completed |
| Local Institution - 0108 | Rochester | New York | 14621 | Active, not recruiting |
| Local Institution - 0374 | Shirley | New York | 11967 | Active, not recruiting |
| Local Institution - 0372 | The Bronx | New York | 10469 | Completed |
| Local Institution - 0274 | Williamsville | New York | 14221 | Withdrawn |
| Local Institution - 0260 | Durham | North Carolina | 27710 | Active, not recruiting |
| Local Institution - 0400 | Cincinnati | Ohio | 45242 | Active, not recruiting |
| Local Institution - 0377 | Cleveland | Ohio | 44111 | Active, not recruiting |
| Local Institution - 0076 | Cleveland | Ohio | 44195 | Active, not recruiting |
| Local Institution - 0376 | Mayfield Heights | Ohio | 44124 | Active, not recruiting |
| Local Institution - 0359 | Allentown | Pennsylvania | 18103 | Completed |
| Local Institution - 0264 | York | Pennsylvania | 17403 | Completed |
| Local Institution - 0223 | Germantown | Tennessee | 38138 | Active, not recruiting |
| Local Institution - 0378 | Abilene | Texas | 79606 | Active, not recruiting |
| Local Institution - 0275 | Houston | Texas | 77030 | Active, not recruiting |
| Local Institution - 0267 | San Antonio | Texas | 78229 | Active, not recruiting |
| Local Institution - 0409 | San Antonio | Texas | 78240 | Active, not recruiting |
| Local Institution - 0207 | Salt Lake City | Utah | 84106 | Active, not recruiting |
| Local Institution - 0297 | Fredericksburg | Virginia | 22408 | Active, not recruiting |
| Local Institution - 0408 | Norfolk | Virginia | 23502 | Active, not recruiting |
| Local Institution - 0399 | Roanoke | Virginia | 24014 | Active, not recruiting |
| Local Institution - 0268 | Seattle | Washington | 98108 | Active, not recruiting |
| Local Institution - 0293 | Seattle | Washington | 98109 | Withdrawn |
| Local Institution - 0097 | Spokane | Washington | 99208 | Withdrawn |
| Local Institution - 0411 | Vancouver | Washington | 98684 | Active, not recruiting |
| Local Institution - 0220 | Madison | Wisconsin | 53792 | Withdrawn |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 210 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05519085, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 29, 2026 · Synced May 6, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05519085 live on ClinicalTrials.gov.