IMpella-Protected cArdiaC Surgery Trial (IMPACT)
Public ClinicalTrials.gov record NCT05529654. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this Trial is to demonstrate the safety and effectiveness of the use of Impella 5.5 in high-risk cardiac surgery patients, with the overall aim to evaluate if using Impella 5.5 with SmartAssist (Impella 5.5) peri-operatively improves early hemodynamics, end-organ function and clinical outcomes in patients with severely reduced LV function undergoing cardiac surgery.
Study identification
- NCT ID
- NCT05529654
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 100 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 21, 2023 (Actual)
- Primary completion
- Nov 4, 2025 (Actual)
- Completion
- Aug 3, 2026 (Actual)
- Last update posted
- Aug 28, 2026
2023 – 2026
United States locations
- U.S. sites
- 20
- U.S. states
- 15
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cardiology Associates Research Group | Jonesboro | Arkansas | 72401 | — |
| Keck School of Medicine | Los Angeles | California | 90033 | — |
| Tri-City Medical Center | San Diego | California | 92056 | — |
| NCH Rooney Heart Institute | Naples | Florida | 34102 | — |
| Emory University Hospital | Atlanta | Georgia | 30322 | — |
| Mass General Hospital | Boston | Massachusetts | 02114 | — |
| Brigham & Women's | Boston | Massachusetts | 02115 | — |
| Minneapolis Heart Institute Foundation/Abbott Northwestern Hospital | Minneapolis | Minnesota | 55407 | — |
| Barnes-Jewish Hospital | St Louis | Missouri | 63110 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| NYU Langone Health | New York | New York | 10016 | — |
| New York- Presbyterian Hospital/ Columbia University Medical Center | New York | New York | 10032 | — |
| Montefiore Medical Center | The Bronx | New York | 10467 | — |
| New Hanover Regional Medical Center | Wilmington | North Carolina | 28401 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Providence St. Vincent Medical Center | Portland | Oregon | 97225 | — |
| Hospital of The University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Centennial Heart Cardiovascular | Nashville | Tennessee | 37203 | — |
| University of Texas Austin Dell Medical School/Ascension Texas | Austin | Texas | 78705 | — |
| Baylor Scott and White - Plano | Plano | Texas | 75093 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05529654, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 28, 2026 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05529654 live on ClinicalTrials.gov.