ClinicalTrials.gov record
Recruiting Phase 2 Interventional

Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma

ClinicalTrials.gov ID: NCT05535166

Public ClinicalTrials.gov record NCT05535166. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 8, 2026, 10:49 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

SJiMB21: Phase 2 Study of Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma

Study identification

NCT ID
NCT05535166
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
St. Jude Children's Research Hospital
Other
Enrollment
130 participants

Conditions and interventions

Interventions

  • Carboplatin Drug
  • Cisplatin Drug
  • Cyclophosphamide Drug
  • Educational and Media Intervention Other
  • Etoposide Drug
  • Filgrastim Drug
  • Irradiation Radiation
  • Methotrexate Drug
  • Ommaya/VPS Procedure
  • Pegfilgrastim Drug
  • SOC, Educational and Media Intervention Other
  • Surgical resection Procedure
  • Topotecan Drug
  • Vincristine Drug

Drug · Other · Radiation + 1 more

Eligibility (public fields only)

Age range
Up to 59 Months
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 19, 2022
Primary completion
Jun 30, 2035
Completion
Jun 30, 2035
Last update posted
Feb 11, 2026

2022 – 2035

United States locations

U.S. sites
10
U.S. states
7
U.S. cities
10
Facility City State ZIP Site status
Lucille Packard Children's Hospital Stanford Palo Alto California 94304 Recruiting
Orlando Health Arnold Palmer Hospital for Children Orlando Florida 32806 Recruiting
St. Joseph's Children's Hospital Tampa Florida 33607 Recruiting
C.S. MOTT Children's Hospital, University of Michigan Ann Arbor Michigan 48109 Recruiting
Children's Hospital and Clinics of Minnesota Minneapolis Minnesota 55404 Recruiting
St. Jude Children's Research Hospital Memphis Tennessee 38105 Recruiting
UT Southwestern Medical Center/Harold C Simmons Comprehensive Cancer Center Dallas Texas 75235 Recruiting
Cook Children's Medical Center Fort Worth Texas 76104 Recruiting
Texas Children's Hospital Houston Texas 77477 Recruiting
Primary Children's Hospital Salt Lake City Utah 84113 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05535166, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 11, 2026 · Synced May 8, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05535166 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →