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Recruiting Phase 1 Interventional

A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors

ClinicalTrials.gov ID: NCT05538130

Public ClinicalTrials.gov record NCT05538130. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 21, 2026, 12:34 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A PHASE 1A/B OPEN-LABEL MASTER STUDY OF PF-07799544 AS A SINGLE-AGENT AND IN COMBINATION WITH OTHER TARGETED AGENTS IN PARTICIPANTS WITH BRAF-MUTANT MELANOMA AND OTHER SOLID TUMORS

Study identification

NCT ID
NCT05538130
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 1
Lead sponsor
Pfizer
Industry
Enrollment
124 participants

Conditions and interventions

Interventions

  • PF-07799544 Drug
  • PF-07799933 Drug

Drug

Eligibility (public fields only)

Age range
16 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 29, 2022
Primary completion
Aug 8, 2027
Completion
Feb 6, 2029
Last update posted
May 19, 2026

2022 – 2029

United States locations

U.S. sites
58
U.S. states
17
U.S. cities
31
Facility City State ZIP Site status
The Kirklin Clinic of UAB Hospital Birmingham Alabama 35233 Recruiting
The University of Alabama at Birmingham Birmingham Alabama 35249 Recruiting
University of Alabama at Birmingham - Phase I Clinical Trials Unit Birmingham Alabama 35249 Recruiting
Highlands Oncology Group, PA Fayetteville Arkansas 72703 Recruiting
Highlands Oncology Group, PA Rogers Arkansas 72758 Recruiting
Highlands Oncology Group, PA Springdale Arkansas 72762 Recruiting
The Angeles Clinic and Research Institute- A Cedars-Sinai Affiliate Los Angeles California 90025 Recruiting
Keck Hospital of USC Los Angeles California 90033 Not yet recruiting
Los Angeles General Medical Center Los Angeles California 90033 Not yet recruiting
USC/Norris Comprehensive Cancer Center Los Angeles California 90033 Not yet recruiting
Keck Medical Center of USC Pasadena Pasadena California 91105 Not yet recruiting
UCSF Helen Diller Family Comprehensive Cancer Center San Francisco California 94143 Recruiting
UCSF Helen Diller Medical Center at Parnassus Heights San Francisco California 94143 Recruiting
UCSF Medical Center, Investigational Pharmacy San Francisco California 94158 Recruiting
The Angeles Clinic and Research Institue, A Cedars-Sinai Affiliate (Emergency Back-up only) Santa Monica California 90404 Recruiting
Moffitt Cancer Center, Richard M. Shulze Family Foundation Outpatient Center Tampa Florida 33612 Recruiting
Moffitt Cancer Center Tampa Florida 33612 Recruiting
Moffitt McKinley Hospital Tampa Florida 33612 Recruiting
Ochsner Clinic Foundation New Orleans Louisiana 70121 Not yet recruiting
Massachusetts General Hospital Boston Massachusetts 02114 Not yet recruiting
Ophthalmic Consultants of Boston Inc (OCB) Boston Massachusetts 02114 Not yet recruiting
Brigham and Women's Hospital Boston Massachusetts 02115 Recruiting
Dana-Farber Cancer Institute Boston Massachusetts 02215 Recruiting
Mass General Waltham Waltham Massachusetts 02451 Not yet recruiting
Brigitte Harris Cancer Pavilion Detroit Michigan 48202 Recruiting
Henry Ford Hospital Detroit Michigan 48202 Recruiting
HealthPartners Frauenshuh Cancer Center Saint Louis Park Minnesota 55426 Not yet recruiting
Methodist Hospital Inpatient Pharmacy Saint Louis Park Minnesota 55426 Not yet recruiting
HealthPartners Cancer Center at regions Hospital Saint Paul Minnesota 55101 Not yet recruiting
Regions Hospital Pharmacy Saint Paul Minnesota 55101 Not yet recruiting
MSK Basking Ridge. Basking Ridge New Jersey 07920 Recruiting
MSK Monmouth. Middletown New Jersey 07748 Recruiting
MSK Bergen. Montvale New Jersey 07645 Recruiting
Optum Medical Care, PC Brewster New York 10509 Not yet recruiting
MSK Commack. Commack New York 11725 Recruiting
MSK Westchester. Harrison New York 10604 Recruiting
Optum Medical Care, PC Mount Kisco New York 10549 Not yet recruiting
Laura & Isaac Perlmutter Cancer Center - NYU ACC New York New York 10016 Recruiting
Laura & Isaac Perlmutter Cancer Center at NYU Langone Health New York New York 10016 Recruiting
NYU Langone Faculty Group Practice New York New York 10016 Recruiting
NYU Langone Medical Center (Tisch Hospital) New York New York 10016 Recruiting
Memorial Sloan Kettering Cancer Center 53rd street. New York New York 10022 Recruiting
Columbia University Irving Medical Center New York New York 10032 Recruiting
Columbia University Medical Center - Neurological Institute of New York New York New York 10032 Recruiting
CUIMC Research Pharmacy New York New York 10032 Recruiting
Memorial Sloan Kettering Cancer Center - Main Campus New York New York 10065 Recruiting
MSK Nassau. Uniondale New York 11553 Recruiting
Cleveland Clinic Taussig Cancer Center Investigational Pharmacy Cleveland Ohio 44106 Recruiting
Cleveland Clinic Taussig Cancer Center Cleveland Ohio 44195 Recruiting
Providence Cancer Institute Franz Clinic Portland Oregon 97213 Recruiting
Providence Portland Medical Center Portland Oregon 97213 Recruiting
UPMC Hillman Cancer Center Pittsburgh Pennsylvania 15232 Not yet recruiting
SCRI Oncology Partners Nashville Tennessee 37203 Recruiting
University of Texas MD Anderson Cancer Center Houston Texas 77030 Recruiting
Fred Hutchinson Cancer Center Seattle Washington 98109 Recruiting
University of Washington Medical Center Seattle Washington 98195 Recruiting
University of Wisconsin Carbone Cancer Center - Eastpark Medical Center Madison Wisconsin 53718 Recruiting
University of Wisconsin Carbone Cancer Center - University Hospital Madison Wisconsin 53792 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 23 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05538130, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 19, 2026 · Synced May 21, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05538130 live on ClinicalTrials.gov.

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