Surgical Myomectomy Followed by Oral Myfembree Versus Standard of Care Trial (SOUL)
Public ClinicalTrials.gov record NCT05538689. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Surgical Myomectomy Followed by Oral Myfembree Versus Standard of Care Trial.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
In this project, the proposition is that the use of daily dosed Myfembree ( a combination of relugolix with estradiol and norethindrone acetate), FDA-approved medication to treat heavy menses fibroid-related symptoms, has the potential to delay the recurrence of fibroid symptoms, prolong the improved quality of life and delay the need for re-intervention after uterine sparing surgery versus the routine standard of care.
Study identification
- NCT ID
- NCT05538689
- Recruitment status
- Withdrawn
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- Not listed
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 19, 2022
- Primary completion
- Oct 23, 2024
- Completion
- Oct 23, 2024
- Last update posted
- Jun 4, 2026
2022 – 2024
United States locations
- U.S. sites
- 6
- U.S. states
- 2
- U.S. cities
- 4
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Chicago South Loop | Chicago | Illinois | 60607 | — |
| University of Chicago River East | Chicago | Illinois | 60611 | — |
| University of Chicago DCAM | Chicago | Illinois | 60637 | — |
| University of Chicago Flossmoor | Flossmoor | Illinois | 60422 | — |
| University of Chicago Orland Park | Orland Park | Illinois | 60462 | — |
| University of Chicago Schererville | Schererville | Indiana | 46375 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05538689, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 4, 2026 · Synced Sep 5, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05538689 live on ClinicalTrials.gov.