Study of SGR-1505 in Mature B-Cell Neoplasms
Public ClinicalTrials.gov record NCT05544019. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1, Open-Label, Multicenter, Dose Escalation Study of SGR-1505 as Monotherapy in Subjects With Mature B-Cell Malignancies
Study identification
- NCT ID
- NCT05544019
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- Schrödinger, Inc.
- Industry
- Enrollment
- 98 participants
Conditions and interventions
Conditions
- ALK-Positive Large B-Cell Lymphoma
- Burkitt Lymphoma
- Chronic Lymphocytic Leukemia
- DLBCL
- DLBCL Germinal Center B-Cell Type
- Duodenal-Type Follicular Lymphoma
- EBV-Positive DLBCL, Nos
- Follicular Lymphoma
- HHV8-Positive DLBCL, Nos
- High-grade B-cell Lymphoma
- IRF4 Gene Rearrangement
- Lymphoplasmacytic Lymphoma
- MALT Lymphoma
- Mantle Cell Lymphoma
- Mature B-Cell Neoplasm
- Nodal Marginal Zone Lymphoma
- Non Hodgkin Lymphoma
- Pediatric-Type Follicular Lymphoma
- Plasmablastic Lymphoma
- Primary Cutaneous Diffuse Large B-Cell Lymphoma
- Primary Cutaneous Follicle Center Lymphoma
- Primary Effusion Lymphoma
- Primary Mediastinal Large B Cell Lymphoma
- Splenic Marginal Zone Lymphoma
- T-Cell/Histiocyte Rich Lymphoma
- Waldenstrom Macroglobulinemia
Interventions
- SGR-1505 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 9, 2023
- Primary completion
- Oct 31, 2027
- Completion
- Oct 31, 2027
- Last update posted
- Feb 12, 2026
2023 – 2027
United States locations
- U.S. sites
- 16
- U.S. states
- 13
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Banner Health - MD Anderson Cancer Center | Gilbert | Arizona | 85234 | Recruiting |
| Christiana Care Hospital - Helen F Graham Cancer Center | Newark | Delaware | 19713 | Recruiting |
| Napa Research | Pompano Beach | Florida | 99064 | Recruiting |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | Recruiting |
| Regional Cancer Care Associates | Hackensack | New Jersey | 07601 | Recruiting |
| Roswell Park Comprehensive Cancer Center | Buffalo | New York | 14203 | Recruiting |
| Weill Cornell | New York | New York | 10065 | Recruiting |
| Montefiore Medical Center | The Bronx | New York | 10467 | Recruiting |
| Duke University | Durham | North Carolina | 27710 | Recruiting |
| Gabrail Cancer & Research Center | Canton | Ohio | 44718 | Recruiting |
| The Ohio State University - The James Cancer Hospital | Columbus | Ohio | 43210 | Recruiting |
| Oregon Health and Science University - Knight Cancer Institute | Portland | Oregon | 97329 | Recruiting |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | Recruiting |
| University of Texas Southwestern | Dallas | Texas | 75390 | Recruiting |
| Fred Hutchinson Cancer Center | Seattle | Washington | 98109 | Recruiting |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 20 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05544019, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 12, 2026 · Synced Apr 29, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05544019 live on ClinicalTrials.gov.