A Study to Evaluate Mezigdomide in Combination With Carfilzomib and Dexamethasone (MeziKD) Versus Carfilzomib and Dexamethasone (Kd) in Participants With Relapsed or Refractory Multiple Myeloma (SUCCESSOR-2)
Public ClinicalTrials.gov record NCT05552976. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Two-stage, Randomized, Multicenter, Open-label Study Comparing Mezigdomide (CC-92480/BMS-986348), Carfilzomib, and Dexamethasone (MeziKD) Versus Carfilzomib and Dexamethasone (Kd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM): SUCCESSOR-2
Study identification
- NCT ID
- NCT05552976
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Bristol-Myers Squibb
- Industry
- Enrollment
- 606 participants
Conditions and interventions
Conditions
Interventions
- Carfilzomib Drug
- Dexamethasone Drug
- Mezigdomide Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 9, 2023
- Primary completion
- Jul 17, 2026
- Completion
- Jul 24, 2029
- Last update posted
- Mar 31, 2026
2023 – 2029
United States locations
- U.S. sites
- 34
- U.S. states
- 20
- U.S. cities
- 32
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Local Institution - 0046 | Mobile | Alabama | 36604 | — |
| Local Institution - 0005 | Cerritos | California | 90703 | — |
| Local Institution - 0190 | Irvine | California | 92618 | — |
| Local Institution - 0187 | Los Angeles | California | 90017 | — |
| Local Institution - 0344 | Santa Rosa | California | 95403 | — |
| Local Institution - 0339 | Stockton | California | 95204 | — |
| Local Institution - 0279 | Newark | Delaware | 19713 | — |
| Local Institution - 0341 | Fort Myers | Florida | 33901 | — |
| Local Institution - 0342 | St. Petersburg | Florida | 33705 | — |
| Local Institution - 0340 | West Palm Beach | Florida | 33401 | — |
| Local Institution - 0348 | Atlanta | Georgia | 30303 | — |
| Local Institution - 0291 | Atlanta | Georgia | 30322 | — |
| Saint Alphonsus Regional Medical Center | Boise | Idaho | 83706 | — |
| Local Institution - 0289 | Annapolis | Maryland | 21401 | — |
| Local Institution - 0204 | Boston | Massachusetts | 02215 | — |
| Local Institution - 0346 | Minneapolis | Minnesota | 55404 | — |
| Local Institution - 0222 | Little Silver | New Jersey | 07739 | — |
| Local Institution - 0199 | The Bronx | New York | 10467 | — |
| Local Institution - 0322 | Cleveland | Ohio | 44106 | — |
| Local Institution - 0172 | Columbus | Ohio | 43214 | — |
| Local Institution - 0321 | Providence | Rhode Island | 02903 | — |
| Local Institution - 0338 | Greer | South Carolina | 29650 | — |
| Local Institution - 0349 | Chattanooga | Tennessee | 37404 | — |
| Local Institution - 0323 | Nashville | Tennessee | 37203 | — |
| Local Institution - 0337 | Fort Worth | Texas | 76104 | — |
| Local Institution - 0328 | Houston | Texas | 77025 | — |
| Local Institution - 0044 | Houston | Texas | 77030 | — |
| Local Institution - 0195 | Temple | Texas | 76508 | — |
| Local Institution - 0345 | Norfolk | Virginia | 23502 | — |
| Local Institution - 0343 | Roanoke | Virginia | 24014 | — |
| Local Institution - 0006 | Tacoma | Washington | 98405 | — |
| Local Institution - 0347 | Vancouver | Washington | 98684 | — |
| Local Institution - 0243 | Morgantown | West Virginia | 26506 | — |
| Local Institution - 0336 | Marshfield | Wisconsin | 54449 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 173 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05552976, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 31, 2026 · Synced May 7, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05552976 live on ClinicalTrials.gov.