ClinicalTrials.gov record
Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Participants With Metastatic Breast Cancer
ClinicalTrials.gov ID: NCT05563220
Public ClinicalTrials.gov record NCT05563220. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced Apr 29, 2026, 11:00 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1b/2, Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Patients With Metastatic Breast Cancer
Study identification
- NCT ID
- NCT05563220
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Stemline Therapeutics, Inc.
- Industry
- Enrollment
- 435 participants
Conditions and interventions
Conditions
Interventions
- Abemaciclib Drug
- Alpelisib Drug
- Capivasertib Drug
- Elacestrant Drug
- Everolimus Drug
- Palbociclib Drug
- Ribociclib Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 23, 2023
- Primary completion
- Dec 26, 2026
- Completion
- Dec 27, 2028
- Last update posted
- Jan 5, 2026
2023 – 2028
United States locations
- U.S. sites
- 45
- U.S. states
- 26
- U.S. cities
- 42
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Dothan Hematology and Oncology | Dothan | Alabama | 36303 | Recruiting |
| Mayo Clinic - Arizona | Phoenix | Arizona | 85054 | Recruiting |
| Highlands Oncology Group | Springdale | Arkansas | 72762 | Recruiting |
| OPN Healthcare (Arcadia Location) | Arcadia | California | 91007 | Withdrawn |
| City of Hope National Medical Center | Duarte | California | 91010 | Not yet recruiting |
| Glendale Adventist | Glendale | California | 91206 | Withdrawn |
| OPN Healthcare (Los Alamitos Location) | Los Alamitos | California | 90720 | Recruiting |
| Cedars Sinai | Los Angeles | California | 90048 | Recruiting |
| UCLA UCLA Hem/Onc - Clinical Research Unit | Los Angeles | California | 90095 | Recruiting |
| UCSF Helen Diller Family Comprehensive Cancer Center | San Francisco | California | 94158 | Recruiting |
| TOI Clinical Research | Whittier | California | 90603 | Completed |
| Rocky Mountain Cancer Centers | Lone Tree | Colorado | 80124 | Recruiting |
| Yale School Of Medicine - Smilow Cancer Hospital - Breast Center | New Haven | Connecticut | 06519 | Withdrawn |
| George Washington Cancer Center | Washington D.C. | District of Columbia | 20037 | Recruiting |
| Advent Health (Florida Hospital) - Altamonte Springs | Altamonte Springs | Florida | 32701 | Recruiting |
| Mayo Clinic - Jacksonville | Jacksonville | Florida | 32224 | Recruiting |
| Ocala Oncology | Ocala | Florida | 34474 | Withdrawn |
| Northside Hospital Atlanta Cancer Care | Cumming | Georgia | 30041 | Withdrawn |
| Northwestern Feinberg Scholl of Medicine Prentice Women's Hospital | Chicago | Illinois | 60611 | Recruiting |
| Fort Wayne Medical Oncology and Hematology | Fort Wayne | Indiana | 46804 | Withdrawn |
| MD Alliance for Multispecialty Research, LLC | Merriam | Kansas | 66204 | Recruiting |
| New England Cancer Specialists | Scarborough | Maine | 04074 | Withdrawn |
| Johns Hopkins School of Medicine | Baltimore | Maryland | 21287 | Recruiting |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | Recruiting |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02215 | Recruiting |
| Barbara Ann Karmanos Cancer Institute | Detroit | Michigan | 48201 | Recruiting |
| Minnesota Oncology Hematology | Minneapolis | Minnesota | 55404 | Withdrawn |
| Mayo Clinic - Rochester | Rochester | Minnesota | 55905 | Recruiting |
| Washington University School of Medicine in St. Louis | St Louis | Missouri | 63110 | Recruiting |
| Astera Cancer Care | East Brunswick | New Jersey | 08816 | Recruiting |
| Summit Medical Group | Florham Park | New Jersey | 07932 | Recruiting |
| Cooperman Barnabas Medical Center | New Brunswick | New Jersey | 08901 | Recruiting |
| NYU Langone Health | New York | New York | 10016 | Recruiting |
| New York Cancer and Blood Specialists | Port Jefferson Station | New York | 11776 | Withdrawn |
| W&IH of RI Breast Health Center of Women and Infants Hospital of Rhode Island | Providence | Rhode Island | 02905 | Recruiting |
| Sarah Cannon Research Institute / Tennessee Oncology | Nashville | Tennessee | 37203 | Recruiting |
| Texas Oncology - Baylor Charles A. Sammons Cancer Center | Dallas | Texas | 75246 | Recruiting |
| MD Anderson Cancer Center Texas | Houston | Texas | 77030 | Recruiting |
| UT Health San Antonio | San Antonio | Texas | 78229 | Recruiting |
| Inova Schar Cancer Institute | Fairfax | Virginia | 22031 | Withdrawn |
| Virginia Cancer Specialists | Fairfax | Virginia | 22031 | Recruiting |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | Recruiting |
| Cancer Care Northwest | Spokane Valley | Washington | 99216 | Recruiting |
| Northwest Medical Specialties (Nwms) - Puyallup - Medical Oncology (Rainier Hematology-Oncology)/Exigent Research Network; LLC | Tacoma | Washington | 98405 | Recruiting |
| University of WI - Carbone Cancer Center (Phase II only) | Madison | Wisconsin | 53792 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 73 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05563220, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 5, 2026 · Synced Apr 29, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05563220 live on ClinicalTrials.gov.