A Study Comparing Teclistamab Monotherapy Versus Pomalidomide, Bortezomib, Dexamethasone (PVd) or Carfilzomib, Dexamethasone (Kd) in Participants With Relapsed or Refractory Multiple Myeloma
Public ClinicalTrials.gov record NCT05572515. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Randomized Study Comparing Teclistamab Monotherapy Versus Pomalidomide, Bortezomib, Dexamethasone (PVd) or Carfilzomib, Dexamethasone (Kd) in Participants With Relapsed or Refractory Multiple Myeloma Who Have Received 1 to 3 Prior Lines of Therapy, Including an Anti-CD38 Monoclonal Antibody and Lenalidomide
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to compare the efficacy of teclistamab with PVd/Kd in Part 1 and to further characterize safety and efficacy of an alternative dosing for teclistamab in Part 2 in participants with relapsed or refractory multiple myeloma.
Study identification
- NCT ID
- NCT05572515
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 614 participants
Conditions and interventions
Conditions
Interventions
- Teclistamab Drug
- Pomalidomide Drug
- Bortezomib Drug
- Dexamethasone Drug
- Carfilzomib Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 29, 2023 (Actual)
- Primary completion
- Oct 13, 2025 (Actual)
- Completion
- Aug 31, 2031 (Estimated)
- Last update posted
- Apr 13, 2026
2023 – 2031
United States locations
- U.S. sites
- 30
- U.S. states
- 20
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alaska Oncology and Hematology LLC | Anchorage | Alaska | 99508 | — |
| Banner MD Anderson Cancer Center | Gilbert | Arizona | 85234 | — |
| Alta Bates Comprehensive Cancer Center | Berkeley | California | 94704 | — |
| MemorialCare Long Beach Medical Center | Long Beach | California | 90806 | — |
| University of California Irvine | Orange | California | 92868 | — |
| PIH Health Hospital | Whittier | California | 90602 | — |
| Rocky Mountain Cancer Centers | Aurora | Colorado | 80218 | — |
| University of Connecticut | Farmington | Connecticut | 06030 | — |
| University of Miami Sylvester Cancer Center | Miami | Florida | 33136 | — |
| Orlando Health Cancer Institute | Orlando | Florida | 32806 | — |
| Cleveland Clinic Florida | Weston | Florida | 33331 | — |
| Mission Cancer Blood | Waukee | Iowa | 50263 | — |
| East Jefferson General Hospital Bone Marrow Transport Clinic | Metairie | Louisiana | 70006 | — |
| Walter Reed National Military Medical Center | Bethesda | Maryland | 20889 | — |
| Maryland Oncology Hematology P A | Silver Spring | Maryland | 20904 | — |
| Boston University Medical Center | Boston | Massachusetts | 02118 | — |
| Saint Lukes Hospital Saint Lukes Cancer Specialists | Chesterfield | Missouri | 63017 | — |
| Cooper Health System MD Anderson Cancer Center at Cooper | Camden | New Jersey | 08103 | — |
| Herbert Irving Comprehensive Cancer Center Columbia University Medical Center | New York | New York | 10032 | — |
| Durham VAMC | Durham | North Carolina | 27705 | — |
| Penn Medicine Lancaster General Health | Lancaster | Pennsylvania | 17601 | — |
| Tennessee Oncology | Nashville | Tennessee | 37203 | — |
| Brooke Army Medical Center | Fort Sam Houston | Texas | 78234 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Michael E DeBakey VA Medical Center | Houston | Texas | 77030 | — |
| Harris Health Smith Clinic | Houston | Texas | 77054 | — |
| Utah Cancer Specialists | Salt Lake City | Utah | 84106 | — |
| Alexander T. Augusta Military Medical Center | Fort Belvoir | Virginia | 22060 | — |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | — |
| NorthWest Medical Specialties, PLLC | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 181 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05572515, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 13, 2026 · Synced Oct 3, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05572515 live on ClinicalTrials.gov.