A Study of Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of KAN-101 in Celiac Disease (ACeD-it)
Public ClinicalTrials.gov record NCT05574010. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1B Open-label/Phase 2 Double-blind Placebo- Controlled Study for Pharmacodynamic (PD) Activity, Pharmacokinetics (PK), Safety, and Tolerability of KAN-101 In Patients With Celiac Disease (CeD)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is to evaluate the Pharmacodynamic (PD), safety, tolerability, Pharmacokinetic (PK), and plasma biomarker response of KAN-101 in participants with Celiac Disease (CeD).
Study identification
- NCT ID
- NCT05574010
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Enrollment
- 128 participants
Conditions and interventions
Conditions
Interventions
- Cohort 1 in Part A Drug
- Cohort 2 in Part A Drug
- Placebo: Group 1 in Part B and Part C Other
- Group 2 in Part B and Part C Drug
- Group 3 in Part B and Part C Drug
- Group 4 in Part B and Part C Drug
Drug · Other
Eligibility (public fields only)
- Age range
- 18 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 15, 2022 (Actual)
- Primary completion
- Nov 29, 2024 (Actual)
- Completion
- May 19, 2025 (Actual)
- Last update posted
- Mar 10, 2026
2022 – 2025
United States locations
- U.S. sites
- 23
- U.S. states
- 17
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35233 | — |
| Anaheim Clinical Trials, LLC | Anaheim | California | 92801 | — |
| GCP Research | St. Petersburg | Florida | 33705 | — |
| Agile Clinical Research Trials | Sandy Springs | Georgia | 30328 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Sneeze, Wheeze & Itch Associates, LLC | Normal | Illinois | 61761 | — |
| Indiana University Health University Hospital | Indianapolis | Indiana | 46202 | — |
| University of Iowa | Iowa City | Iowa | 52242 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Prism Research LLC dba Nucleus Network | Saint Paul | Minnesota | 55114 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Quality Clinical Research | Omaha | Nebraska | 68114 | — |
| Celiac Disease Center at Columbia University | New York | New York | 10032 | — |
| North Carolina Clinical Research | Raleigh | North Carolina | 27607 | — |
| Aventiv Research, Inc. d/b/a Centricity Research | Columbus | Ohio | 43213 | — |
| Great Lakes Gastroenterology Research, LLC | Mentor | Ohio | 44060 | — |
| Northshore Gastroenterology Research, LLC | Westlake | Ohio | 44145 | — |
| Penn State Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37212 | — |
| The University of Texas Health Science Center at Houston | Houston | Texas | 77030 | — |
| Digestive Research of Central Texas | Waco | Texas | 76712 | — |
| Advanced Research Institute | Ogden | Utah | 84405 | — |
| Velocity Clinical Research, Salt Lake City | West Jordan | Utah | 84088 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 13 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05574010, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 10, 2026 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05574010 live on ClinicalTrials.gov.