ClinicalTrials.gov record
Active, not recruiting Phase 1 Interventional

Study of RYZ101 in Combination With SoC in Subjects With SSTR+ ES-SCLC

ClinicalTrials.gov ID: NCT05595460

Public ClinicalTrials.gov record NCT05595460. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Apr 29, 2026, 9:11 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase 1b Single Arm, Open-label Trial of RYZ101 in Combination With Carboplatin + Etoposide + Atezolizumab in Subjects With Somatostatin Receptor Expressing (SSTR+) Extensive Stage Small Cell Lung Cancer (ES-SCLC)

Study identification

NCT ID
NCT05595460
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 1
Lead sponsor
RayzeBio, Inc.
Industry
Enrollment
21 participants

Conditions and interventions

Interventions

  • Atezolizumab Drug
  • Carboplatin Drug
  • Etoposide Drug
  • RYZ101 Dose Level -1 Drug
  • RYZ101 Dose Level 2 Drug
  • RYZ101 Dose Level 3 Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 9, 2022
Primary completion
Jun 30, 2027
Completion
Jun 30, 2027
Last update posted
Apr 12, 2026

2022 – 2027

United States locations

U.S. sites
12
U.S. states
9
U.S. cities
12
Facility City State ZIP Site status
Research Facility Los Angeles California 90024
Research Facility San Francisco California 94158
Research Facility Jacksonville Florida 32224
Research Facility Miami Florida 33136
Research Facility Orlando Florida 32806
Research Facility Iowa City Iowa 52242
Reserach Facility Lexington Kentucky 40536
Research Facility Grand Rapids Michigan 49503
Research Facility Rochester Minnesota 55905
Research Facility St Louis Missouri 63130
Research Facility Omaha Nebraska 68130
Research Facility Salt Lake City Utah 84112

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05595460, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 12, 2026 · Synced Apr 29, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05595460 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →