A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202)
Public ClinicalTrials.gov record NCT05600426. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III Randomized Trial Comparing Unrelated Donor Bone Marrow Transplantation With Immune Suppressive Therapy for Newly Diagnosed Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202)
Study identification
- NCT ID
- NCT05600426
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Boston Children's Hospital
- Other
- Enrollment
- 53 participants
Conditions and interventions
Conditions
Interventions
- Cyclophosphamide Drug
- Fludarabine Drug
- Immunosuppressive Therapy (IST) Procedure
- Matched Unrelated Donor Hematopoetic Stem Cell Transplant Procedure
- Methotrexate Drug
- cyclosporine Drug
- horse anti-thymocyte globulin (ATG) Drug
- low-dose total body irradiation (TBI) Radiation
- rabbit anti-thymocyte globulin (ATG) Drug
Drug · Procedure · Radiation
Eligibility (public fields only)
- Age range
- 0 Years to 25 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 24, 2023
- Primary completion
- Nov 30, 2029
- Completion
- Nov 30, 2029
- Last update posted
- May 18, 2026
2023 – 2029
United States locations
- U.S. sites
- 50
- U.S. states
- 31
- U.S. cities
- 47
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35249 | — |
| Phoenix Children's Hospital | Phoenix | Arizona | 85016 | — |
| Arkansas | Little Rock | Arkansas | 72202 | — |
| Loma Linda | Loma Linda | California | 92354 | — |
| Children's Hospital Los Angeles | Los Angeles | California | 90027 | — |
| UCLA | Los Angeles | California | 90095 | — |
| Children's Hospital & Research Center Oakland | Oakland | California | 94609 | — |
| Children's Hospital of Orange County | Orange | California | 92868 | — |
| Stanford | Palo Alto | California | 94304 | — |
| Rady Children's Hospital San Diego | San Diego | California | 92123 | — |
| University of California San Francisco | San Francisco | California | 94158 | — |
| Children's Hospital Colorado | Aurora | Colorado | 80045 | — |
| Yale University | New Haven | Connecticut | 06520 | — |
| Nemours Children's Hospital, Delaware | Wilmington | Delaware | 19803 | — |
| Children's National Hospital | Washington D.C. | District of Columbia | 20010 | — |
| University of Florida | Gainesville | Florida | 32610 | — |
| University of Miami | Miami | Florida | 33136 | — |
| Nicklaus Children's Hospital | Miami | Florida | 33155 | — |
| Johns Hopkins All Children's Hospital | St. Petersburg | Florida | 33701 | — |
| Children's Hospital of Atlanta/Emory | Atlanta | Georgia | 30322 | — |
| Ann & Robert H. Lurie Children's Hospital of Chicago | Chicago | Illinois | 60611 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| Indiana University Hospital/Riley Hospital for Children | Indianapolis | Indiana | 46202 | — |
| Children's Hospital NOLA | New Orleans | Louisiana | 70118 | — |
| Maine Health | Scarborough | Maine | 04074 | — |
| Boston Children's Hospital | Boston | Massachusetts | 02115 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Helen DeVos Children's Hospital | Grand Rapids | Michigan | 49503 | — |
| Mayo Clinic Rochestser | Rochester | Minnesota | 55902 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | — |
| Washington University in St. Louis | St Louis | Missouri | 63110 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Roswell Park Comprehensive Cancer Center | Buffalo | New York | 14263 | — |
| Cohen Children's Medical Center of New York | New Hyde Park | New York | 11040 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| University of North Carolina | Chapel Hill | North Carolina | 27599 | — |
| Levine Children's Hospital | Charlotte | North Carolina | 28203 | — |
| Duke University | Durham | North Carolina | 27705 | — |
| Nationwide Children's Hospital | Columbus | Ohio | 43205 | — |
| Oregon Health & Science University | Portland | Oregon | 97239 | — |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| St. Jude Children's Research Hospital | Memphis | Tennessee | 38105 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37203 | — |
| Children's Medical Center Dallas | Dallas | Texas | 75235 | — |
| Texas Children's Hospital | Houston | Texas | 77030 | — |
| Methodist Healthcare | San Antonio | Texas | 78229 | — |
| University of Utah/Primary Children's Hospital | Salt Lake City | Utah | 84112 | — |
| Children's Hospital of the King's Daughter | Norfolk | Virginia | 23507 | — |
| Fred Hutchinson Cancer Center | Seattle | Washington | 98109 | — |
| University of Wisconsin | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05600426, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 18, 2026 · Synced May 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05600426 live on ClinicalTrials.gov.