ClinicalTrials.gov record
Recruiting Phase 2 Interventional

Loncastuximab Tesirine and Rituximab Followed by DA-EPOCH-R for Treating Patients With High-Risk Diffuse Large B-cell Lymphoma

ClinicalTrials.gov ID: NCT05600686

Public ClinicalTrials.gov record NCT05600686. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 8, 2026, 10:43 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2 Study of Loncastuximab Tesirine and Rituximab (Lonca-R) Followed by DA-EPOCH-R in Previously Untreated High-Risk Diffuse Large B-Cell Lymphoma

Study identification

NCT ID
NCT05600686
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Joseph Tuscano
Other
Enrollment
24 participants

Conditions and interventions

Interventions

  • Cyclophosphamide Drug
  • Doxorubicin Drug
  • Etoposide Drug
  • Loncastuximab Tesirine Biological
  • Prednisone Drug
  • Rituximab Biological
  • Vincristine Drug

Drug · Biological

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 23, 2023
Primary completion
Jan 31, 2026
Completion
Jan 31, 2028
Last update posted
Nov 24, 2025

2023 – 2028

United States locations

U.S. sites
2
U.S. states
1
U.S. cities
2
Facility City State ZIP Site status
University of California Davis Comprehensive Cancer Center Sacramento California 95817 Recruiting
UC San Diego Moores Cancer Center San Diego California 92037 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05600686, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 24, 2025 · Synced May 8, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05600686 live on ClinicalTrials.gov.

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