Efficacy and Safety of MK-1942 as an Adjunct Therapy in Participants With Mild to Moderate Alzheimer's Disease Dementia (MK-1942-008)
Public ClinicalTrials.gov record NCT05602727. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2a/2b Randomized, Placebo-Controlled Clinical Study To Evaluate The Safety And Efficacy Of MK-1942 As Adjunctive Therapy In Participants With Mild To Moderate Alzheimer's Disease Dementia
Study identification
- NCT ID
- NCT05602727
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Merck Sharp & Dohme LLC
- Industry
- Enrollment
- 99 participants
Conditions and interventions
Conditions
Interventions
- MK-1942 Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 55 Years to 90 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 1, 2022
- Primary completion
- Sep 26, 2023
- Completion
- Sep 26, 2023
- Last update posted
- Dec 9, 2024
2022 – 2023
United States locations
- U.S. sites
- 22
- U.S. states
- 15
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Banner Alzheimer's Institute ( Site 0017) | Phoenix | Arizona | 85006 | — |
| Neurology Center of North Orange County ( Site 0039) | Fullerton | California | 92835 | — |
| California Neuroscience Research, LLC ( Site 0058) | Sherman Oaks | California | 91403 | — |
| JEM Research Institute ( Site 0013) | Atlantis | Florida | 33462 | — |
| Velocity Clinical Research, Hallandale Beach ( Site 0025) | Hallandale | Florida | 33009 | — |
| K2 Medical Research ( Site 0057) | Maitland | Florida | 32751 | — |
| Premier Clinical Research Institute ( Site 0038) | Miami | Florida | 33122 | — |
| Collier Neurologic Specialists ( Site 0045) | Naples | Florida | 34105 | — |
| Atlanta Center for Medical Research ( Site 0044) | Atlanta | Georgia | 30331 | — |
| iResearch Atlanta ( Site 0016) | Decatur | Georgia | 30030 | — |
| Alexian Brothers Medical Center ( Site 0011) | Elk Grove Village | Illinois | 60007 | — |
| Tandem Clinical Research ( Site 0055) | Marrero | Louisiana | 70072 | — |
| Global Medical Institutes LLC; Princeton Medical Institute ( Site 0053) | Princeton | New Jersey | 08540 | — |
| Advanced Memory Research Institute of New Jersey ( Site 0027) | Toms River | New Jersey | 08755 | — |
| Richmond Behavioral Associates ( Site 0008) | Staten Island | New York | 10314 | — |
| AMC Research, LLC ( Site 0004) | Matthews | North Carolina | 28105 | — |
| NeuroScience Research Center ( Site 0009) | Canton | Ohio | 44718 | — |
| Summit Headlands ( Site 0018) | Portland | Oregon | 97210 | — |
| Grayline Research Center ( Site 0003) | Wichita Falls | Texas | 76309 | — |
| The Memory Clinic ( Site 0054) | Bennington | Vermont | 05201 | — |
| Re:Cognition Health ( Site 0031) | Fairfax | Virginia | 22031 | — |
| Northwest Clinical Research Center ( Site 0056) | Bellevue | Washington | 98007 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 52 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05602727, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 9, 2024 · Synced May 8, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05602727 live on ClinicalTrials.gov.