Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy

ClinicalTrials.gov ID: NCT05615844

Public ClinicalTrials.gov record NCT05615844. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Apr 22, 2026, 8:51 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized Controlled Trial Comparing Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy for the Management of Severe Open Tibia Fracture Wounds

Study identification

NCT ID: NCT05615844
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: University of Maryland, Baltimore; Other
Enrollment: 312 participants

Conditions and interventions

Conditions

Open tíbia Fracture

Interventions

Antibiotic Cement Bead Pouch Drug
Negative Pressure Wound Therapy Device

Drug · Device

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Not listed

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Nov 4, 2023
Primary completion: Mar 30, 2027
Completion: Sep 30, 2027
Last update posted: Mar 9, 2026

2023 – 2027

United States locations

U.S. sites: 28
U.S. states: 20
U.S. cities: 26

Facility	City	State	ZIP	Site status
Dignity Health Chandler Regional Medical Center	Chandler	Arizona	85224	Recruiting
University of California, Davis	Davis	California	95616	Recruiting
University of Southern California	Los Angeles	California	90033	Recruiting
Cedars-Sinai Medical Center	Los Angeles	California	90048	Recruiting
University of California, Irvine	Orange	California	92868	Recruiting
Yale University	New Haven	Connecticut	06520	Recruiting
University of Florida	Gainesville	Florida	32611	Recruiting
University of Miami	Miami	Florida	33146	Recruiting
Indiana University	Indianapolis	Indiana	46202	Recruiting
University of Maryland, R Adams Cowley Shock Trauma Center	Baltimore	Maryland	21201	Recruiting
University of Maryland Capital Region Health	Largo	Maryland	20774	Recruiting
Beth Israel Deaconess Medical Center	Boston	Massachusetts	02215	Recruiting
University of Mississippi	University	Mississippi	38677	Recruiting
Bryan Medical Center	Lincoln	Nebraska	68506	Recruiting
University Medical Center of Southern Nevada	Las Vegas	Nevada	89102	Withdrawn
Dartmouth-Hitchcock Medical Center	Lebanon	New Hampshire	03766	Recruiting
Sanford Medical Center	Fargo	North Dakota	58103	Recruiting
University of Cincinnati	Cincinnati	Ohio	45219	Recruiting
Bon Secours Mercy Health	Cincinnati	Ohio	45237	Recruiting
Slocum Center	Eugene	Oregon	97401	Recruiting
Ortegon Health & Science University	Portland	Oregon	97239	Recruiting
St. Luke's University Health Network	Bethlehem	Pennsylvania	18015	Recruiting
Prisma Health - Midlands	Columbia	South Carolina	29203	Recruiting
Prisma Health	Greenville	South Carolina	29605	Recruiting
Sanford Health	Sioux Falls	South Dakota	57104	Recruiting
University of Utah	Salt Lake City	Utah	84112	Recruiting
Inova Fairfax	Falls Church	Virginia	22042	Recruiting
University of Wisconsin	Madison	Wisconsin	53792	Withdrawn

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT05615844, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Mar 9, 2026 · Synced Apr 22, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05615844 live on ClinicalTrials.gov.

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