A Study to Evaluate Next-Generation Sequencing (NGS) Testing and Monitoring of B-cell Recovery to Guide Management Following Chimeric Antigen Receptor T-cell (CART) Induced Remission in Children and Young Adults With B Lineage Acute Lymphoblastic Leu...

ClinicalTrials.gov ID: NCT05621291

Public ClinicalTrials.gov record NCT05621291. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 9, 2026, 1:08 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Pilot Trial to Evaluate Next-Generation Sequencing (NGS) Testing and Monitoring of B-Cell Recovery to Guide Management Following CAR T-cell Induced Remission in Pediatric Patients With B Lineage Acute Lymphoblastic Leukemia

Study identification

NCT ID: NCT05621291
Recruitment status: Recruiting
Study type: Interventional
Phase: Not applicable
Lead sponsor: National Cancer Institute (NCI); NIH
Enrollment: 60 participants

Conditions and interventions

Conditions

Interventions

NGS testing Diagnostic Test

Diagnostic Test

Eligibility (public fields only)

Age range: 1 Year to 25 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: May 12, 2026
Primary completion: Dec 30, 2026
Completion: Dec 30, 2027
Last update posted: May 7, 2026

2026 – 2027

United States locations

U.S. sites: 8
U.S. states: 7
U.S. cities: 7

Facility	City	State	ZIP	Site status
Children's Hospital of Los Angeles	Los Angeles	California	90027	Recruiting
Children's National Medical Center	Washington D.C.	District of Columbia	20010	Recruiting
Children's Healthcare of Atlanta	Atlanta	Georgia	30329	Not yet recruiting
National Institutes of Health Clinical Center	Bethesda	Maryland	20892	Recruiting
Dana-Farber/Boston Children s Hospital	Boston	Massachusetts	02115	Not yet recruiting
Huntsman Cancer Institute, University of Utah	Salt Lake City	Utah	84112	Recruiting
Seattle Children's, University of Washington	Seattle	Washington	98105	Recruiting
Fred Hutchinson Cancer Research Center	Seattle	Washington	98109	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT05621291, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted May 7, 2026 · Synced May 9, 2026

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The complete protocol, eligibility criteria, and contact information for NCT05621291 live on ClinicalTrials.gov.

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