Efficacy, Safety, and Tolerability of COMP360 in Participants With TRD
Public ClinicalTrials.gov record NCT05624268. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Multicentre, Randomised, Double-blind, Placebo-controlled Study to Investigate the Efficacy, Safety, and Tolerability of COMP360 in Participants With Treatment-resistant Depression
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Efficacy, Safety, and Tolerability of a single administration of COMP360 in participants with treatment-resistant depression (TRD)
Study identification
- NCT ID
- NCT05624268
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 258 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 23, 2023
- Primary completion
- May 27, 2025
- Completion
- Apr 14, 2026
- Last update posted
- Aug 9, 2026
2023 – 2026
United States locations
- U.S. sites
- 40
- U.S. states
- 19
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Arizona College of Medicine - Tuscon | Tuscon | Arizona | 85724 | — |
| ProScience Research Group | Culver City | California | 90230 | — |
| Collaborative Neuroscience Network, LLC | Garden Grove | California | 92845 | — |
| Kadima Neuropsychiatry Institute | La Jolla | California | 92037 | — |
| University California San Diego | La Jolla | California | 92037 | — |
| California Center for Psychedelic Therapy | Los Angeles | California | 90004 | — |
| CalNeuro Research Group, Inc | Los Angeles | California | 90025 | — |
| Clarity Clinical Research, LLC | Los Angeles | California | 90064 | — |
| ATP Clinical Research, Inc. | Orange | California | 92868 | — |
| Artemis Institute for Clinical Research | San Diego | California | 92103 | — |
| Lumos Clinical Research Center | San Jose | California | 95124 | — |
| Stanford University | Stanford | California | 94305 | — |
| ASCLEPES Research Centers | Thousand Oaks | California | 93012 | — |
| Comprehensive Psychiatric Care | Norwich | Connecticut | 06360 | — |
| Clinical Neurosciecne Solutions, Inc. dba CNS Healthcare | Orlando | Florida | 32801 | — |
| APG Research, LLC | Orlando | Florida | 32803 | — |
| DMI Health Care Group, Inc | Tampa | Florida | 33782 | — |
| Meridien Research/Accel Research | Tampa | Florida | 33803 | — |
| Psych Atlanta | Atlanta | Georgia | 30060 | — |
| Emory University | Atlanta | Georgia | 30329-2209 | — |
| Uptown Research Institute, LLC | Chicago | Illinois | 60640 | — |
| Sheppard Pratt Health System | Baltimore | Maryland | 21044 | — |
| CBH Health, LLC | Gaithersburg | Maryland | 20877 | — |
| Pharmasite Research, Inc | Pikesville | Maryland | 21208 | — |
| University of Massachusetts Medical School | North Worcester | Massachusetts | 01655 | — |
| University of Minnesota | Minneapolis | Minnesota | 55416 | — |
| University of Missouri | Columbia | Missouri | 65212 | — |
| Midwest Research Group | Saint Charles | Missouri | 63304 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Alivation Research, LLC. | Lincoln | Nebraska | 68526 | — |
| Bio Behavioral Health | Toms River | New Jersey | 08755 | — |
| New York State Psychiatric Institute | New York | New York | 10032 | — |
| The Medical Research Network, LLC | New York | New York | 10128 | — |
| Insight Clinical Trials, LLC | Beachwood | Ohio | 44122 | — |
| Neuro-Behaviroral Clinical Research, Inc. | North Canton | Ohio | 44720 | — |
| Rivus Wellness & Research Institute | Oklahoma City | Oklahoma | 73112 | — |
| Global Medical Institutes, LLC, Scranton Medical Institute | Moosic | Pennsylvania | 18507 | — |
| UT Health Science Center at Houston (UTHSC-H) | Houston | Texas | 77030 | — |
| Cedar Clinical Research | Draper | Utah | 84020 | — |
| Core Clinical Research | Everett | Washington | 98201 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05624268, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 9, 2026 · Synced Sep 28, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05624268 live on ClinicalTrials.gov.