FXR Effect on Severe Alcohol-Associated Hepatitis (FRESH) Study
Public ClinicalTrials.gov record NCT05639543. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2a, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Dose-Escalation, Proof-of-Concept Study Evaluating the Safety, Tolerability, Efficacy and Pharmacokinetics of INT-787 in Subjects With Severe Alcohol Associated Hepatitis
Study identification
- NCT ID
- NCT05639543
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Intercept Pharmaceuticals
- Industry
- Enrollment
- 67 participants
Conditions and interventions
Conditions
Interventions
- INT-787 Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 14, 2022
- Primary completion
- Feb 9, 2026
- Completion
- Feb 9, 2026
- Last update posted
- May 4, 2026
2022 – 2026
United States locations
- U.S. sites
- 20
- U.S. states
- 14
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of California, San Francisco-Fresno | Fresno | California | 93701 | — |
| Stanford Healthcare | Palo Alto | California | 94305 | — |
| UC Davis Medical Center | Sacramento | California | 95817 | — |
| Clinical Translational Research Site | Miami | Florida | 33136 | — |
| Tampa General Medical Group | Tampa | Florida | 33606 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Mercy Medical Center | Baltimore | Maryland | 21202 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | — |
| UMass Memorial Medical Center | Worcester | Massachusetts | 01655 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Northwell Health Center for Liver Disease and Transplantation | Manhasset | New York | 11030 | — |
| Columbia University Medical Center/New York Presbyterian Hospital | New York | New York | 10032 | — |
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Vanderbilt Digestive Disease Center | Nashville | Tennessee | 37232 | — |
| The Liver Institute at Methodist Dallas Medical Center | Dallas | Texas | 75203 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| University of Utah Hospital | Salt Lake City | Utah | 84132 | — |
| VCU Health Clinical Research Services Unit | Richmond | Virginia | 23298 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 9 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05639543, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 4, 2026 · Synced May 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05639543 live on ClinicalTrials.gov.