[18F]PI-2620 Phase 3 Histopathological Study
Public ClinicalTrials.gov record NCT05641688. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-label, Non-randomized, Multi-center Pivotal Phase 3 Study to Evaluate the Efficacy and Safety of PET Imaging With [18F]PI-2620 for the Detection of Tau Deposition When Compared to Post-mortem Histopathology (ADvance)
Study identification
- NCT ID
- NCT05641688
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Life Molecular Imaging Ltd
- Industry
- Enrollment
- 200 participants
Conditions and interventions
Conditions
Interventions
- [18F]PI-2620 Drug
Drug
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 30, 2022
- Primary completion
- May 31, 2027
- Completion
- May 31, 2027
- Last update posted
- Apr 28, 2026
2022 – 2027
United States locations
- U.S. sites
- 25
- U.S. states
- 10
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Barrow Neurological Institute | Phoenix | Arizona | 85013 | Recruiting |
| Banner Sun Health Research Institute | Sun City | Arizona | 85352 | Recruiting |
| UC Los Angeles | Los Angeles | California | 90095 - 7370 | Recruiting |
| Esperanza Clinical | Murrieta | California | 92562 | Recruiting |
| Sutter Health | San Francisco | California | 94114 | Recruiting |
| Galiz Research | Hialeah | Florida | 33016 | Recruiting |
| UF College of Medicine - Jacksonville | Jacksonville | Florida | 32209 | Withdrawn |
| K2 Medical Research | Lady Lake | Florida | 32159 | Recruiting |
| K2 Medical Research | Maitland | Florida | 32751 | Recruiting |
| ClinCloud Research | Melbourne | Florida | 32940 | Recruiting |
| Miami Jewish Health Systems | Miami | Florida | 33137 | Recruiting |
| The Roskamp Institute | Sarasota | Florida | 34243 | Terminated |
| Charter Research | Winter Park | Florida | 32792 | Recruiting |
| Alzheimer's Disease Center | Braintree | Massachusetts | 02184 | Recruiting |
| Headlands Research | Plymouth | Massachusetts | 02360 | Withdrawn |
| Be Well Clinical Studies | Lincoln | Nebraska | 68616 | Withdrawn |
| Darthmouth-Hitchcock Medical Center | Lebanon | New Hampshire | 07366 | Recruiting |
| Velocity Clinical Research | East Syracuse | New York | 13057 | Recruiting |
| Ichor Research | Syracuse | New York | 13219 | Recruiting |
| American Carolina Clinical Research LLC | Charlotte | North Carolina | 28273 | Terminated |
| Insight Clinical Trials LLC | Beachwood | Ohio | 44131 | Recruiting |
| Valley Medical Research | Centerville | Ohio | 45459 | Recruiting |
| Baylor Research Institute | Dallas | Texas | 75231 | Recruiting |
| Sante Clinical Research | Kerrville | Texas | 78028 | Recruiting |
| Be Well Clinical Studies | Round Rock | Texas | 78681 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05641688, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 28, 2026 · Synced May 6, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05641688 live on ClinicalTrials.gov.