A Research Study to Evaluate the Effects of a New Oral Medicine Called Cenerimod in Adults With Systemic Lupus Erythematosus
Public ClinicalTrials.gov record NCT05648500. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Evaluate the Efficacy, Safety, and Tolerability of Cenerimod in Adult Subjects With Moderate-to-Severe Systemic Lupus Erythematosus (SLE) on Top of Background Therapy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The goal of this clinical trial is to see how well cenerimod reduces symptoms of Systemic Lupus Erythematosus in adult patients with moderate to severe symptoms. The main questions it aims to answer are: * How well cenerimod works on top of the treatment already being administered. * How safe cenerimod is for adult patients with Systemic Lupus Erythematosus. Researchers will compare one dose of cenerimod and a placebo to see how well cenerimod works when it is added to the treatment already being administered. In this research study approximately 210 participants will receive cenerimod and approximately 210 participants will receive placebo for 12 months.
Study identification
- NCT ID
- NCT05648500
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 470 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 13, 2022 (Actual)
- Primary completion
- Mar 31, 2027 (Estimated)
- Completion
- Sep 30, 2027 (Estimated)
- Last update posted
- Sep 15, 2026
2022 – 2027
United States locations
- U.S. sites
- 22
- U.S. states
- 11
- U.S. cities
- 19
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| California Research Institute | Huntington Park | California | 90255 | — |
| University of Colorado Denver | Aurora | Colorado | 80045 | — |
| Clinical Research of West Florida, Inc. | Clearwater | Florida | 33765 | — |
| Omega Research MetroWest, LLC | DeBary | Florida | 32713 | — |
| Alloy Clinical Research, LLC | Kissimmee | Florida | 34741 | — |
| SouthCoast Research Center, Inc. | Miami | Florida | 33136 | — |
| Allied Biomedical Research Institute | Miami | Florida | 33155 | — |
| Professional research Center INC | Miami | Florida | 33172 | — |
| IRIS Research and Development, LLC | Plantation | Florida | 33324-2736 | — |
| Augusta University | Augusta | Georgia | 30912 | — |
| Advance Quality Medical Research | Orland Park | Illinois | 60462 | — |
| Accurate Clinical Research Inc. - Lake Charles | Lake Charles | Louisiana | 70605 | — |
| Louisiana State University School of Medicine section of Rheumatology | New Orleans | Louisiana | 70112 | — |
| Axon Clinical Research -Baltimore | Baltimore | Maryland | 21237 | — |
| Bronx Care Health and Wellness Center | The Bronx | New York | 10457 | — |
| DJL Clinical Research, PLLC | Charlotte | North Carolina | 28210 | — |
| University of Oklahoma College of Medicine | Oklahoma City | Oklahoma | 73117 | — |
| Accurate Clinical Research Inc. | Baytown | Texas | 77521 | — |
| Rheumatology Care Center, PLLC | Bellaire | Texas | 77041 | — |
| Houston MD Medspa and Wellness Clinic | Houston | Texas | 77084 | — |
| Accurate Clinical Research Inc. | Houston | Texas | 77089 | — |
| Sun Research Institute | San Antonio | Texas | 78215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 176 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05648500, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 15, 2026 · Synced Oct 28, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05648500 live on ClinicalTrials.gov.