Letrozole in Uterine Leiomyosarcoma
Public ClinicalTrials.gov record NCT05649956. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized Phase II Study of Letrozole Versus Observation in Patients With Newly Diagnosed Uterine Leiomyosarcoma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a clinical trial to test letrozole in patients with uterine leiomyosarcoma. The main question is will treatment with letrozole extend progression-free survival in patients. Patients will receive 2/5 mg of letrozole daily.
Study identification
- NCT ID
- NCT05649956
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 40 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 16, 2024
- Primary completion
- Jul 29, 2028
- Completion
- Jul 29, 2029
- Last update posted
- Jul 29, 2026
2024 – 2029
United States locations
- U.S. sites
- 34
- U.S. states
- 17
- U.S. cities
- 30
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Colorado Cancer Center - Anschutz Cancer Pavilion | Aurora | Colorado | 80045 | Recruiting |
| Highlands Ranch Hospital | Highlands Ranch | Colorado | 80129 | Recruiting |
| Broward Health Medical Center | Fort Lauderdale | Florida | 33316 | Recruiting |
| Mount Sinai Comprehensive Cancer Center | Miami Beach | Florida | 33140 | Recruiting |
| Winship Cancer Institute, Emory Hospital | Atlanta | Georgia | 30322 | Recruiting |
| Endeavor Health - Kellogg Cancer Center | Evanston | Illinois | 60201 | Recruiting |
| Indiana University Melvin and Bren Simon Comprehensive Cancer Center | Indianapolis | Indiana | 46202 | Recruiting |
| LSU Health Sciences Center | New Orleans | Louisiana | 70112 | Recruiting |
| WK Physician Network-Gynecologic Oncology Associates | Shreveport | Louisiana | 71103 | Recruiting |
| University of Massachusetts Memorial Medical Center | Worcester | Massachusetts | 01605 | Recruiting |
| ProMedica Charles and Virginia Hickman Hospital, | Adrian | Michigan | 49221 | Recruiting |
| ProMedica Monroe Regional Hospital | Monroe | Michigan | 48162 | Recruiting |
| University of Minnesota | Minneapolis | Minnesota | 55455 | Recruiting |
| Women's Cancer Center of Nevada | Las Vegas | Nevada | 89106 | Recruiting |
| Women's Cancer Center of Nevada | Las Vegas | Nevada | 89511 | Recruiting |
| Atlantic Health System | Morristown | New Jersey | 07960 | Recruiting |
| Overlook Medical Center | Summit | New Jersey | 07901 | Recruiting |
| University of New Mexico Comprehensive Cancer Center | Albuquerque | New Mexico | 87131 | Recruiting |
| East Carolina University Health Medical Center | Greenville | North Carolina | 27834 | Recruiting |
| OhioHealth Arthur G.H. Bing, MD Cancer Center | Columbus | Ohio | 43214 | Recruiting |
| OhioHealth Research Institute | Columbus | Ohio | 43214 | Recruiting |
| OhioHealth Riverside Methodist Hospital | Columbus | Ohio | 43214 | Recruiting |
| OhioHealth Grant Medical Center | Columbus | Ohio | 43215 | Recruiting |
| ProMedica Defiance Regional Hospital | Defiance | Ohio | 43512 | Recruiting |
| ProMedica Fostoria Community Hospital | Fostoria | Ohio | 44830 | Recruiting |
| ProMedica Memorial Hospital | Fremont | Ohio | 43420 | Recruiting |
| OhioHealth Marion General Hospital | Marion | Ohio | 43302 | Recruiting |
| Bay Park Hospital | Oregon | Ohio | 43616 | Recruiting |
| ProMedica Laboratories Perrysburg | Perrysburg | Ohio | 43551 | Recruiting |
| ProMedica Flower Hospital | Sylvania | Ohio | 43560 | Recruiting |
| ProMedica Toledo Hospital | Toledo | Ohio | 43606 | Recruiting |
| University of Oklahoma Health Stephenson Cancer Center | Oklahoma City | Oklahoma | 73104 | Recruiting |
| Asplundh Cancer Pavilion | Willow Grove | Pennsylvania | 19090 | Recruiting |
| Woman and Infants Hospital of Rhode Island | Providence | Rhode Island | 02905 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05649956, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 29, 2026 · Synced Sep 5, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05649956 live on ClinicalTrials.gov.